UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    Form 13F

                               Form 13F COVER PAGE

Report for the Calendar Year or Quarter Ended: March 31, 2006

Check here if Amendment [ ]; Amendment Number:
                                               -------
This Amendment (Check only one.):               [ ] is a restatement.
                                                [ ] adds new holdings entries.

Institutional Investment Manager Filing this Report:

Name:      Burke & Herbert Bank & Trust Co.
           -----------------------------------------------------
Address:   PO Box 268
           Alexandria, VA 22314
           -----------------------------------------------------

Form 13F File Number: 28-05313
                      --------

The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing the report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables, are considered integral parts of this form.

Person Signing this Report on Behalf of Reporting Manager:

Name:   /s/ Judith A. Cagnon
        -------------------------
Title:  Vice President
        -------------------------
Phone:  703-549-6600
        -------------------------

Signature,  Place,  and  Date  of  Signing:

/s/ Judith A. Cagnon                  Alexandria, VA                   4/6/2006
--------------------                  --------------                   --------
    [Signature]                       [City, State]                     [Date]

Report  Type  (Check  only  one):

[X]     13F HOLDINGS REPORT. (Check here if all holdings of this reporting
        manager are reported in this report.)

[ ]     13F NOTICE. (Check here if no holdings reported are in this report,
        and all holdings are reported by other reporting manager(s).)

[ ]     13F COMBINATION REPORT. (Check here if a portion of the holdings for
        this reporting manager are reported in this report and a portion are
        reported by other reporting manager(s).)

List of Other Managers Reporting for this Manager:
[If there are no entries in this list, omit this section.]

13F File Number  Name

28-____________   ________________________________________
         [Repeat as necessary.]



                              Form 13F SUMMARY PAGE

Report Summary:
Number of Other Included Managers:                 0
                                         -----------
Form 13F Information Table Entry Total:          178
                                         -----------
Form 13F Information Table Value Total:     $113,641
                                         -----------
                                         (thousands)


List of Other Included Managers:

Provide a numbered list of the name(s) and 13F file number(s) of all
institutional investment managers with respect to which this report is filed,
other than the manager filing this report.

[If there are no entries in this list, state "NONE" and omit the column headings
and list entries.]

NONE





                                               FORM 13F INFORMATION TABLE

                                                           VALUE  SHARES/ SH/ PUT/ INVSTMT  OTHER    VOTING AUTHORITY
        NAME OF ISSUER          TITLE OF CLASS    CUSIP   (x$1000) PRN AMT PRN CALL DSCRETN MANAGERS  SOLE  SHARED NONE
------------------------------ ---------------- --------- -------- ------- --- ---- ------- -------- ------ ------ ----
                                                                                  
INGERSOLL-RAND COMPANY LTD     CL A             G4776G101      309    7400 SH       SHRD               7400      0    0
AT&T INC                       COM              00206R102      386   14273 SH       SOLE              14273      0    0
AT&T INC                       COM              00206R102      113    4174 SH       SHRD               4174      0    0
ABBOTT LABS                    COM              002824100      648   15250 SH       SOLE              15250      0    0
ABBOTT LABS                    COM              002824100      166    3910 SH       SHRD               3910      0    0
AIR PRODS & CHEMS INC          COM              009158106       54     800 SH       SOLE                800      0    0
AIR PRODS & CHEMS INC          COM              009158106      148    2200 SH       SHRD               2200      0    0
ALLIED CAP CORP NEW            COM              01903Q108      215    7025 SH       SHRD               7025      0    0
ALLTEL CORP                    COM              020039103      211    3262 SH       SOLE               3262      0    0
ALLTEL CORP                    COM              020039103      193    2974 SH       SHRD               2974      0    0
ALTRIA GROUP INC               COM              02209S103     1524   21501 SH       SOLE              21501      0    0
ALTRIA GROUP INC               COM              02209S103       46     650 SH       SHRD                650      0    0
AMERICAN EXPRESS CO            COM              025816109      293    5571 SH       SOLE               5571      0    0
AMERICAN EXPRESS CO            COM              025816109       37     700 SH       SHRD                700      0    0
AMERICAN INTL GROUP INC        COM              026874107      791   11966 SH       SOLE              11966      0    0
AMERICAN INTL GROUP INC        COM              026874107      115    1733 SH       SHRD               1733      0    0
AMGEN INC                      COM              031162100       44     600 SH       SOLE                600      0    0
AMGEN INC                      COM              031162100      242    3325 SH       SHRD               3325      0    0
AMSOUTH BANCORPORATION         COM              032165102     2726  100772 SH       SOLE             100772      0    0
AMSOUTH BANCORPORATION         COM              032165102       92    3400 SH       SHRD               3400      0    0
ANADARKO PETE CORP             COM              032511107      112    1109 SH       SOLE               1109      0    0
ANADARKO PETE CORP             COM              032511107      227    2249 SH       SHRD               2249      0    0
ANHEUSER BUSCH COS INC         COM              035229103      157    3671 SH       SOLE               3671      0    0
ANHEUSER BUSCH COS INC         COM              035229103       49    1150 SH       SHRD               1150      0    0
APACHE CORP                    COM              037411105      210    3200 SH       SHRD               3200      0    0
AUTOMATIC DATA PROCESSING I    N COM            053015103       73    1600 SH       SOLE               1600      0    0
AUTOMATIC DATA PROCESSING I    N COM            053015103      279    6100 SH       SHRD               6100      0    0
BP PLC                         SPONSORED ADR    055622104     1087   15767 SH       SOLE              15767      0    0
BP PLC                         SPONSORED ADR    055622104      247    3581 SH       SHRD               3581      0    0
BANK OF AMERICA CORPORATION    COM              060505104     1016   22320 SH       SOLE              22320      0    0
BANK OF AMERICA CORPORATION    COM              060505104      519   11401 SH       SHRD              11401      0    0
BANK NEW YORK INC              COM              064057102      426   11808 SH       SOLE              11808      0    0
BANK NEW YORK INC              COM              064057102      103    2848 SH       SHRD               2848      0    0
BELLSOUTH CORP                 COM              079860102      814   23487 SH       SOLE              23487      0    0
BELLSOUTH CORP                 COM              079860102       87    2515 SH       SHRD               2515      0    0
BIOMET INC                     COM              090613100      208    5850 SH       SOLE               5850      0    0
BOEING CO                      COM              097023105      227    2910 SH       SOLE               2910      0    0
BOEING CO                      COM              097023105       31     400 SH       SHRD                100    300    0
BRISTOL MYERS SQUIBB CO        COM              110122108      384   15619 SH       SOLE              15619      0    0
BRISTOL MYERS SQUIBB CO        COM              110122108       72    2920 SH       SHRD               2920      0    0
BURKE&HERBERT B&T ALEXANDRI    A COM            121331102    21745   11080 SH       SOLE              11080      0    0
BURKE&HERBERT B&T ALEXANDRI    A COM            121331102     2657    1354 SH       SHRD               1354      0    0
CIGNA CORP                     COM              125509109      661    5060 SH       SOLE               5060      0    0
CVS CORP                       COM              126650100       27     900 SH       SOLE                900      0    0
CVS CORP                       COM              126650100      341   11400 SH       SHRD              11400      0    0
CHEVRON CORP NEW               COM              166764100     1308   22568 SH       SOLE              22568      0    0
CHEVRON CORP NEW               COM              166764100      573    9876 SH       SHRD               9876      0    0
CISCO SYS INC                  COM              17275R102      431   19897 SH       SOLE              19897      0    0
CISCO SYS INC                  COM              17275R102       57    2613 SH       SHRD               2613      0    0
CITIGROUP INC                  COM              172967101     1203   25475 SH       SOLE              25475      0    0
CITIGROUP INC                  COM              172967101      460    9729 SH       SHRD               9729      0    0
COCA COLA CO                   COM              191216100      898   21449 SH       SOLE              21449      0    0
COCA COLA CO                   COM              191216100       63    1500 SH       SHRD               1500      0    0
COLGATE PALMOLIVE CO           COM              194162103      233    4080 SH       SOLE               4080      0    0
COLGATE PALMOLIVE CO           COM              194162103      128    2250 SH       SHRD               2250      0    0
COMPASS BANCSHARES INC         COM              20449H109      250    4937 SH       SOLE               4937      0    0
DELL INC                       COM              24702R101      323   10850 SH       SOLE              10850      0    0
DELL INC                       COM              24702R101       49    1650 SH       SHRD               1650      0    0
DISNEY WALT CO                 COM DISNEY       254687106      549   19692 SH       SOLE              19692      0    0
DISNEY WALT CO                 COM DISNEY       254687106      290   10400 SH       SHRD              10400      0    0
DOMINION RES INC VA NEW        COM              25746U109      676    9790 SH       SOLE               9790      0    0
DOMINION RES INC VA NEW        COM              25746U109      129    1875 SH       SHRD               1875      0    0
DU PONT E I DE NEMOURS & CO    COM              263534109      920   21796 SH       SOLE              21796      0    0
DU PONT E I DE NEMOURS & CO    COM              263534109      324    7683 SH       SHRD               7683      0    0
DUKE ENERGY CORP               COM              264399106       67    2300 SH       SOLE               2300      0    0
DUKE ENERGY CORP               COM              264399106      213    7300 SH       SHRD               7300      0    0
DUN & BRADSTREET CORP DEL N    E COM            26483E100      537    7000 SH       SHRD               7000      0    0
E M C CORP MASS                COM              268648102       11     800 SH       SOLE                800      0    0
E M C CORP MASS                COM              268648102      238   17460 SH       SHRD              17460      0    0
EXXON MOBIL CORP               COM              30231G102     5293   86969 SH       SOLE              86969      0    0
EXXON MOBIL CORP               COM              30231G102     2304   37860 SH       SHRD              37860      0    0
FPL GROUP INC                  COM              302571104      278    6918 SH       SOLE               6918      0    0
FPL GROUP INC                  COM              302571104       24     590 SH       SHRD                590      0    0
FEDERAL HOME LN MTG CORP       COM              313400301      482    7900 SH       SOLE               7900      0    0
FEDERAL NATL MTG ASSN          COM              313586109      575   11181 SH       SOLE              11181      0    0
FEDERAL NATL MTG ASSN          COM              313586109       43     833 SH       SHRD                833      0    0
FEDERATED DEPT STORES INC DE   COM              31410H101      119    1625 SH       SOLE               1625      0    0
FEDERATED DEPT STORES INC DE   COM              31410H101      114    1557 SH       SHRD               1557      0    0
GANNETT INC                    COM              364730101      202    3375 SH       SOLE               3375      0    0
GANNETT INC                    COM              364730101       46     775 SH       SHRD                775      0    0
GENERAL ELECTRIC CO            COM              369604103     5873  168855 SH       SOLE             168855      0    0
GENERAL ELECTRIC CO            COM              369604103     1124   32312 SH       SHRD              32312      0    0
GLAXOSMITHKLINE PLC            SPONSORED ADR    37733W105      202    3871 SH       SOLE               3871      0    0
GLAXOSMITHKLINE PLC            SPONSORED ADR    37733W105       17     328 SH       SHRD                328      0    0
HEWLETT PACKARD CO             COM              428236103      915   27807 SH       SOLE              27807      0    0
HEWLETT PACKARD CO             COM              428236103      533   16210 SH       SHRD              16210      0    0
HOME DEPOT INC                 COM              437076102      305    7200 SH       SOLE               7200      0    0
HOME DEPOT INC                 COM              437076102      154    3639 SH       SHRD               3639      0    0
HONEYWELL INTL INC             COM              438516106      247    5780 SH       SOLE               5780      0    0
HONEYWELL INTL INC             COM              438516106      299    7000 SH       SHRD               7000      0    0
HUNTINGTON BANCSHARES INC      COM              446150104      277   11498 SH       SOLE              11498      0    0
INTEL CORP                     COM              458140100      584   30028 SH       SOLE              30028      0    0
INTEL CORP                     COM              458140100      143    7368 SH       SHRD               6568    800    0
INTERNATIONAL BUSINESS MACHS   COM              459200101      960   11638 SH       SOLE              11638      0    0
INTERNATIONAL BUSINESS MACHS   COM              459200101      343    4154 SH       SHRD               4154      0    0
ISHARES TR                     LEHMAN AGG BND   464287226      237    2390 SH       SOLE               2390      0    0
ISHARES TR                     DJ US TOTL MKT   464287846      265    4184 SH       SOLE               4184      0    0
JP MORGAN CHASE & CO           COM              46625H100      556   13345 SH       SOLE              13345      0    0
JP MORGAN CHASE & CO           COM              46625H100      113    2724 SH       SHRD               2724      0    0
JOHNSON & JOHNSON              COM              478160104     3461   58435 SH       SOLE              58435      0    0
JOHNSON & JOHNSON              COM              478160104      284    4800 SH       SHRD               4800      0    0
KIMBERLY CLARK CORP            COM              494368103      362    6259 SH       SOLE               6259      0    0
KIMBERLY CLARK CORP            COM              494368103       87    1500 SH       SHRD               1100    400    0
LOWES COS INC                  COM              548661107       87    1350 SH       SOLE               1350      0    0
LOWES COS INC                  COM              548661107      390    6050 SH       SHRD               6050      0    0
MANULIFE FINL CORP             COM              56501R106      437    6969 SH       SOLE               6969      0    0
MARATHON OIL CORP              COM              565849106      229    3000 SH       SHRD               3000      0    0
MARRIOTT INTL INC NEW          CL A             571903202      258    3754 SH       SOLE               3754      0    0
MARRIOTT INTL INC NEW          CL A             571903202       34     500 SH       SHRD                500      0    0
MCDONALDS CORP                 COM              580135101      238    6938 SH       SOLE               6938      0    0
MEDCO HEALTH SOLUTIONS INC     COM              58405U102      224    3923 SH       SOLE               3923      0    0
MEDCO HEALTH SOLUTIONS INC     COM              58405U102       23     403 SH       SHRD                403      0    0
MEDTRONIC INC                  COM              585055106      311    6130 SH       SOLE               6130      0    0
MEDTRONIC INC                  COM              585055106      104    2049 SH       SHRD               2049      0    0
MERCK & CO INC                 COM              589331107      918   26054 SH       SOLE              26054      0    0
MERCK & CO INC                 COM              589331107      366   10386 SH       SHRD              10386      0    0
MERRILL LYNCH & CO INC         COM              590188108      377    4781 SH       SHRD               4781      0    0
MICROSOFT CORP                 COM              594918104      437   16044 SH       SOLE              16044      0    0
MICROSOFT CORP                 COM              594918104      784   28825 SH       SHRD              28825      0    0
MOODYS CORP                    COM              615369105      457    6400 SH       SHRD               6400      0    0
MORGAN STANLEY                 COM NEW          617446448      206    3283 SH       SOLE               3283      0    0
MORGAN STANLEY                 COM NEW          617446448       49     787 SH       SHRD                787      0    0
MOTOROLA INC                   COM              620076109      405   17696 SH       SOLE              17696      0    0
MOTOROLA INC                   COM              620076109       92    4000 SH       SHRD               4000      0    0
NORFOLK SOUTHERN CORP          COM              655844108     1074   19865 SH       SOLE              19865      0    0
NORFOLK SOUTHERN CORP          COM              655844108      103    1900 SH       SHRD               1900      0    0
NORTHROP GRUMMAN CORP          COM              666807102      202    2962 SH       SOLE               2962      0    0
NORTHROP GRUMMAN CORP          COM              666807102       27     400 SH       SHRD                400      0    0
OMNICOM GROUP INC              COM              681919106      201    2410 SH       SOLE               2410      0    0
ORACLE CORP                    COM              68389X105        4     300 SH       SOLE                300      0    0
ORACLE CORP                    COM              68389X105      159   11600 SH       SHRD              11600      0    0
PPG INDS INC                   COM              693506107      210    3317 SH       SOLE               3317      0    0
PEPSICO INC                    COM              713448108     1130   19547 SH       SOLE              19547      0    0
PEPSICO INC                    COM              713448108      400    6920 SH       SHRD               6920      0    0
PFIZER INC                     COM              717081103     1383   55501 SH       SOLE              55501      0    0
PFIZER INC                     COM              717081103      401   16093 SH       SHRD              16093      0    0
PITNEY BOWES INC               COM              724479100      274    6382 SH       SOLE               6382      0    0
PITNEY BOWES INC               COM              724479100       27     633 SH       SHRD                633      0    0
PROCTER & GAMBLE CO            COM              742718109      801   13899 SH       SOLE              13899      0    0
PROCTER & GAMBLE CO            COM              742718109       83    1440 SH       SHRD               1440      0    0
PROTECTIVE LIFE CORP           COM              743674103    11564  232488 SH       SOLE             232488      0    0
ROCKWELL AUTOMATION INC        COM              773903109      223    3100 SH       SOLE               3100      0    0
ROCKWELL AUTOMATION INC        COM              773903109       65     900 SH       SHRD                900      0    0
ROCKWELL COLLINS INC           COM              774341101      147    2600 SH       SOLE               2600      0    0
ROCKWELL COLLINS INC           COM              774341101       94    1660 SH       SHRD               1660      0    0
ROYAL DUTCH SHELL PLC          SPONS ADR A      780259206      397    6374 SH       SOLE               6374      0    0
SARA LEE CORP                  COM              803111103      281   15737 SH       SOLE              15737      0    0
SARA LEE CORP                  COM              803111103       88    4900 SH       SHRD               4900      0    0
SCHLUMBERGER LTD               COM              806857108      207    1634 SH       SOLE               1634      0    0
SCHLUMBERGER LTD               COM              806857108      405    3200 SH       SHRD               3200      0    0
SOUTHERN CO                    COM              842587107      184    5618 SH       SOLE               5618      0    0
SOUTHERN CO                    COM              842587107       90    2745 SH       SHRD               2745      0    0
SPACE PROPULSION SYS INC       COM              846192102        3   16250 SH       SOLE              16250      0    0
SUNTRUST BKS INC               COM              867914103      317    4360 SH       SOLE               4360      0    0
TARGET CORP                    COM              87612E106      129    2476 SH       SOLE               2476      0    0
TARGET CORP                    COM              87612E106      208    3997 SH       SHRD               3997      0    0
TEXAS INSTRS INC               COM              882508104      222    6842 SH       SOLE               6842      0    0
TEXAS INSTRS INC               COM              882508104      316    9726 SH       SHRD               9726      0    0
3M CO                          COM              88579Y101      858   11333 SH       SOLE              11333      0    0
3M CO                          COM              88579Y101      157    2077 SH       SHRD               2077      0    0
UNITED TECHNOLOGIES CORP       COM              913017109      209    3602 SH       SOLE               3602      0    0
UNITED TECHNOLOGIES CORP       COM              913017109      236    4075 SH       SHRD               4075      0    0
UNITEDHEALTH GROUP INC         COM              91324P102      327    5850 SH       SOLE               5850      0    0
UNITEDHEALTH GROUP INC         COM              91324P102       61    1100 SH       SHRD               1100      0    0
VERIZON COMMUNICATIONS         COM              92343V104      906   26594 SH       SOLE              26594      0    0
VERIZON COMMUNICATIONS         COM              92343V104      372   10917 SH       SHRD              10917      0    0
VERSAR INC                     COM              925297103      326   84700 SH       SOLE              84700      0    0
WACHOVIA CORP 2ND NEW          COM              929903102     1082   19313 SH       SOLE              19313      0    0
WACHOVIA CORP 2ND NEW          COM              929903102       36     643 SH       SHRD                643      0    0
WAL MART STORES INC            COM              931142103      787   16651 SH       SOLE              16651      0    0
WAL MART STORES INC            COM              931142103      232    4907 SH       SHRD               4907      0    0
WASHINGTON MUT INC             COM              939322103       32     740 SH       SOLE                740      0    0
WASHINGTON MUT INC             COM              939322103      207    4863 SH       SHRD               4863      0    0
WELLPOINT INC                  COM              94973V107      527    6800 SH       SHRD               6800      0    0
WELLS FARGO & CO NEW           COM              949746101      626    9800 SH       SOLE               9800      0    0
WELLS FARGO & CO NEW           COM              949746101       72    1126 SH       SHRD               1126      0    0
WYETH                          COM              983024100     1360   28030 SH       SOLE              28030      0    0
WYETH                          COM              983024100      520   10717 SH       SHRD              10717      0    0