Filing under Rule 425 under the Securities

Act of 1933 and deemed filed under Rule

14a-12 of the Securities Exchange Act of

1934

Filing by: Jazz Pharmaceuticals, Inc.

Subject Company: Jazz Pharmaceuticals,

Inc.

SEC File No. of Jazz Pharmaceuticals, Inc.:

001-33500

Ami Fadia:

Hello. Thanks for joining us. The next presentation is from Jazz Pharmaceuticals. I’m Ami Fadia, the (inaudible) tech pharma analyst at UBS and it’s my pleasure to invite Bruce Cozadd, the CEO at Jazz. Following the presentation we’ll have a breakout session at the Broadway Room. Thanks.

BruceCozadd:

Good morning, everyone. Thank you, Ami, and UBS for the opportunity to present this morning. I’m particularly pleased to have the opportunity to present this morning as we announced an important transaction yesterday and this will be a good chance to give all of you an update on that.

Before I get into the presentation, let me remind you, as always, that we’ll make some forward-looking statements during this presentation. Those are subject to the occurrence of a number of risk factors that you can read about in our SEC filings. And in this case, those risk factors also include risk factors related to our potential transaction, including timing, closing and integration. And since we are between announcement and closing of a transaction, I’ll also point you to the SEC website for a series of filings that we and our partner will make over the coming months. Please see those filings for additional information.

Well, before I get to the transaction, let me remind you of the strategy we’ve been talking about now for the past year, a strategy that I think makes sense for the Company and explains our interest in this transaction. The core of our strategy has been, and remains, to build on our success with Xyrem. Xyrem is our lead product and we believe it still offers substantial growth potential in narcolepsy. And the core to our strategy remains optimizing the value of that franchise.

The second pillar of our strategy is building on our strong commercial business and our strong commercial infrastructure by adding additional on-market or near-market products.

The third element of our strategy is, over time, to build and sustain a pipeline of smart R&D investments; investments in R&D programs that are a good fit with our specialty commercial focus, products that are differentiated and can be sold to a concentrated group of physicians that can be reached effectively with our sales force. As part of this strategy, we are currently recruiting for a head of R&D who will help lead these efforts.

And all of these strategic priorities are built over a base, which is our culture, our entrepreneurial ownership-based culture of the Company. And that means making smart resource allocation decisions across these elements of our strategy; smart investments in continuing to grow and defend the Xyrem franchise, smart investments in new products and smart investments in R&D.

So, the transaction we announced yesterday is a merger with Azur Pharma. And let me tell you why we think this transaction makes so much sense. First of all, it provides us an expanded group of products, a more diversified CNS and women’s health revenue line. It

provides us with increased scale and a platform for future growth. Part of doing this transaction was not to look at what one transaction makes sense, but to set ourselves up to be able to do additional transactions in the future. It gives us a stronger base on which to execute our R&D strategy. And with the entire management team of Azur Pharma coming over to join the combined company, I think it will strengthen our management team.

On the financial side, this transaction is expected to be accretive to our adjusted after-tax EPS. And we have given some forward-looking statements here about expecting over $475 million in revenue and $200 million in cash flow in the first 12 months of combined operations. The company should have $0.25 billion in cash at closing, a very strong balance sheet and no debt.

A couple words about the transaction itself. This transaction will be effected in such a way that the Jazz Pharmaceuticals, Inc. shareholders will own just less than 80% and the Azur Pharma shareholders will own just more than 20% of the combined Jazz Pharmaceuticals plc, which will based in Ireland.

In terms of shareholder votes that are required, we do have voting agreements in place with virtually all of the Azur shareholders and 43% of the Jazz shareholders. The Board of Directors will be comprised of our current Board, with the addition of Seamus Mulligan, the Chairman and CEO of Azur. The management team will include all of the current Jazz and Azur management teams, including myself, Kate Falberg, our CFO who’s with me here today, Seamus, and other key members of the Azur team, including Eunan Maguire, David Brabazon, Fintan Keegan and Mike Kelly. We anticipate closing in the first quarter.

In addition to the portfolio of products, Azur brings us strong expertise in CNS and women’s health. Their approximately 170 employees are split among three US sales forces in pain, psychiatry and women’s health. That comprises 105 of their employees, as well as a strong medical affairs team and a relatively lean home office split among Dublin and Philadelphia. They also do have a lower-risk development pipeline, including some lifecycle management programs.

On the right-hand side you see their net sales growth, which reached over $80 million in 2010. We’re forecasting for 2011 sales in the $95 million to $100 million range. That’s with a gross margin of 80% to 85% and expected EBITDA of $27 million to $31 million.

When you add those revenues to our already given guidance for Jazz Pharmaceuticals’ revenues, you see on the right how those revenues would split among the Jazz and Azur products. You can see that Xyrem will remain a significant driver of the overall Company’s performance.

Let’s talk about a couple of the key Azur products, starting with Prialt for chronic pain. This product had sales in 2010 of approximately $20 million, though Azur did not have the product for the entire year, acquiring it in May. This is a formulation of the synthetic peptides aconitine in an intrathecal pump. And we see this product as similar to Xyrem in many ways. It certainly requires a high-touch sales capability with a heavy clinical emphasis. Like Xyrem, we think there’s substantial room for growth with the product currently representing less than 3% of the available pain market pumps. And we see it as having a long franchise life due to intellectual property and other protection. Azur does have worldwide rights to this product, with European rights licensed to Eisai.

The next product is FazaClo with 2010 sales of $37 million. This is an orally disintegrated clozapine tablet approved for the management of treatment-resistant schizophrenic. The product has achieved a 10% prescription share, despite the fact that it

competes in a large genericized clozapine market. Azur did launch a higher-dose version of FazaClo about a year ago and has switched over 20% from their lower dose strengths through the first half of this year. Doctors tell the company they appreciate the dosing flexibility and lower pill burden for patients due to the higher-dosage strengths.

There are generic filers against FazaClo. In a recent settlement with Teva, it would allow for a launch of the lower dosage form in mid-2012 and the higher dosage form in 2015. Azur does have two different formulations of clozapine in its pipeline.

Turning to the women’s health business, which is comprised of a number of different brands, there were two 2010 sales of about $27 million with growth led by Elestrin, a topical gel ERT therapy with long patent life and a new promotional model.

Okay. Let me now spend a few minutes on the Jazz Pharmaceuticals base business and give you an update on that; starting, of course, with Xyrem. Xyrem’s been experiencing terrific growth. You see here our recently announced second quarter results of $56 million in net sales. We gave guidance at the end of our — on our second quarter call at the end of July of $215 million to $225 million for 2011. And you can see that part of the reason for that growth is the improving volume growth of the product, where we’ve seen an acceleration in that volume growth with double-digit year-over-year volume growth in each of the last two quarters. I’ll also point out that we did recently take a price increase on Xyrem of just over 19% on September 1st.

Xyrem is the only FDA-approved product for the treatment of two major symptoms of narcolepsy, cataplexy and excessive daytime sleepiness. It’s been on the market since 2002 and is marketed ex-US by our partners, UCB in Europe and Valeant in Canada. It’s currently used in about 8,700 patients, often in combination with stimulant therapy, often Provigil or Nuvigil. And it’s distributed under a very tightly controlled REMS called our Xyrem Success Program.

If we think about narcolepsy, this is an orphan condition and very debilitating for the patients. Although it’s estimated that narcolepsy affects 125,000 to 200,000 patients in the United States, we believe only 50,000 of those patients are diagnosed and treated. The key symptoms are cataplexy, which is a sudden loss in muscle tone associated with an emotional stimulus. This can be a slight sagging of your face or loss of all muscle control and collapsing to the ground.

Excessive daytime sleepiness is present in all narcolepsy patients. This is not just being tired as you sit through another boring presentation at an investor conference. This is a real inability to go through your day without feeling the sudden need and the irresistible urge to take naps. People with severe, excessive daytime sleepiness really have a tough time holding down a job or maintaining relationships.

If we look at how Xyrem affects these two key symptoms, on the left we see a trial where we showed improvement in excessive daytime sleepiness. It’s measured by the Epworth Sleepiness Scale. And it’s important to note in this trial patients could be on stimulant therapy throughout the trial. So, you’re really looking here at benefit above and beyond benefits you would get from stimulant therapy.

On the right-hand side we look at the effect on cataplexy, measuring the weekly number of cataplexy episodes with the 9 gram dose of Xyrem, providing a 69% median reduction in cataplexy attacks. So, what we see from this slide is that Xyrem is very effective in treating the two key symptoms of narcolepsy.

On the AE side there are a number of AEs associated with Xyrem use, the most common of which include nausea, dizziness and headache. There is a black box warning for

Xyrem. It is a CNS depressant and should not be used in combination with alcohol or other CNS depressants. The black box warning for Xyrem, as well as the other products with black box warnings, are included on the product websites. And if you go to our website and look at a copy of this presentation, you’ll find them there as well.

We have very strong IP protection covering Xyrem with nine patents, seven of which are Orange Book listed. A number of these patents relate specifically to the restricted distribution system and we believe provide very unique protection for the product. You’ll see a number of those patents have issued in the past two years. So, you should know that we remain committed to aggressively pursuing and defending intellectual property protection for Xyrem.

Xyrem enjoys a very strong reimbursement coverage with relatively low rates of prior authorizations required, and with the majority of our patients having monthly out-of-pocket costs of less than $50. On the right you see the make-up of the payers for the product. And I will point out that we distribute a fair amount of product free of charge to patients who can’t afford it.

As we talk about the opportunity to continue growing Xyrem, we’ve launched a number of initiatives designed to improve our market penetration over time, taking us up from those 8,700 out of 50,000 diagnosed patients who currently are on Xyrem treatment. Our new initiatives include adding additional physician targets for our sales force, physicians that we know are treating narcolepsy and prescribing stimulants, but who had not been called on previously by our sales force. By improving the education we provide through the REMS, making sure that physicians and our pharmacy are doing a good job of educating patients about the safe use of the product and what to expect when initiating therapy.

We have a number of other patient services that have been rolled out, including more contact with nurses, including a welcome call and frequent calls during the period when they’re initiating therapy. Also, a brand new patient mentoring program, giving new Xyrem patients the chance to talk to other patients who’ve had experience with Xyrem. These are volunteers who are not paid for their services. And we also have a number of patient assistance programs in place designed to make sure that Xyrem is available to patients who need it, not patients who can afford it.

Let me wrap up the discussion of our business with a look at our guidance for 2011. Again, this guidance is current as of the end of July. We’re not updating it today.

You can see that we’re projecting very strong top line growth with guidance this year of sales between $247 million and $260 million. That represents approximately a 50% to a 60% increase in sales. And given the relatively modest growth in spending at the Company, we see tremendous earnings leverage in our model. That 50% to 60% top line growth is reflected in a more than doubling of our adjusted EPS. You see here adjusted net income guidance of $145 million to $153 million and adjusted EPS guidance of $3.15 to $3.25. We do provide a reconciliation of adjusted net and adjusted EPS back to GAAP figures, again, in an appendix to this presentation.

So, let me conclude by just reiterating my enthusiasm for the transaction we announced yesterday. We believe the merger with Azur provides compelling strategic, commercial, organizational and financial benefits for our company, positions us very well to achieve our vision to help more patients and to continue to build shareholder value. Thank you very much.

And I believe we have a Q&A in a separate room starting soon, the Broadway Room. Thank you.