FORM 6-K
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
Report of Foreign Private Issuer
Pursuant to Rule 13s - 16 or 15d - 16 of
the Securities Exchange Act of 1934
For the month of May 2006
Acambis plc
(Translation of registrant's name into English)
Peterhouse Technology Park
100 Fulbourn Road
Cambridge CB1 9PT
England
(address of principal executive offices)
(Indicate by check mark whether the registrant files or will file annual
reports under cover of Form 20-F or Form 40-F
Forms 20-F X Form 40-F
Indicate by check mark whether the registrant by furnishing the information
contained in this Form also thereby furnishing the information to the
Commission pursuant to Rule 12g3-2(b) under the
Securities Exchange Act of 1934).
Yes No X
(if "Yes" is marked, indicate below the file number assigned to the registrant
in connection with Rule 12g3-2(b): 82- ).
Enclosure:
1st Quarter Results
Results for the first quarter ended 31 March 2006
Cambridge, UK and Cambridge, Massachusetts - 9 May 2006 - Acambis plc
("Acambis") (LSE: ACM, NASDAQ: ACAM) announces its results for the three months
ended 31 March 2006.
Summary of the year to date
> R&D programmes progressing well:
o ChimeriVax-JE:
- Pivotal Phase 3 trials fully recruited
- Regulatory approvals received for first of two paediatric trials
in India
o ChimeriVax-West Nile: dose-ranging component of Phase 2 trial fully
recruited
o C. difficile: Phase 1 trial in elderly subjects fully recruited
o R&D expenditure increased in line with expectations; significant
investment made in progressing ChimeriVax-JE Phase 3 trials ahead of
schedule
> ACAM2000:
o Submission of Biologics License Application to US Food and Drug
Administration completed
o Active discussions ongoing with CDC on warm-base manufacturing for US
Government
> MVA3000:
o Continuing to progress through stages of US Government procurement
process; contract award expected around end of second quarter
o International Trade Commission hearing on dispute with Bavarian Nordic
underway; scope narrowed to patent dispute
> Strong sales of Vivotif(R) typhoid vaccine suggest successful customer
retention
> Chairman to stand down later in 2006
> Cash and cash equivalents of GBP49.8m at 31 March 2006
Key trading highlights*
Three months ended
31 March
2006 2005
Revenue GBP6.0m GBP6.0m
R&D costs GBP9.8m GBP7.2m
Loss before tax GBP(11.4)m GBP(5.8)m
Basic loss per share (10.5)p (4.1)p
Basic loss per ADR $(0.36) $(0.15)
* Prepared under the Group's accounting policies based on International
Financial Reporting Standards
Gordon Cameron, Chief Executive Officer of Acambis, said:
"Since the beginning of 2006, we have continued to make good progress in our
development programmes, including completing recruitment of subjects into our
pivotal Phase 3 ChimeriVax-JE trials and submitting the ACAM2000 product licence
application to the US FDA. We are looking forward to further pipeline progress
in the coming months and to important decisions on the US Government smallpox
vaccine contracts we are pursuing."
A conference call for analysts will be held today at 9.00 am BST. For details,
contact Mo Noonan at Financial Dynamics on telephone number +44 (0) 20 7269
7116. An instant replay of the call will be available until 16 May 2006 on
telephone number UK: +44 (0) 20 7365 8427 and US: + 1 (617) 801 6888. The pin
code is 47328347. A webcast of the call will also be available via Acambis'
website at www.acambis.com. The webcast replay will be available for 12 months
until 9 May 2007.
Chairman's statement
OVERVIEW
Since the beginning of the year, we have made good progress in our clinical
trials and in our efforts to secure additional contracts in the smallpox vaccine
arena.
During the period we had a particularly heavy level of investment in the
pipeline, which ensured our key proprietary programmes continued on track. This
included achieving full recruitment of subjects in the Phase 1 trial of our C.
difficile vaccine, the dose-ranging component of the Phase 2 trial of
ChimeriVax-West Nile and the two Phase 3 trials of ChimeriVax-JE, the latter
being completed ahead of schedule. The level of our R&D investment reflects the
fact that our pipeline is now becoming increasingly advanced and as we continue
to progress our proprietary programmes towards commercialisation we will be
evaluating partnering opportunities.
In terms of the smallpox franchise, we are making good progress towards agreeing
a warm-base manufacturing contract with the US Government and are continuing
through the stages of the US Modified Vaccinia Ankara (MVA) procurement process.
In April, we completed submission of the Biologics License Application (BLA) to
apply for licensure of ACAM2000 in the US. In addition, the first hearing in the
MVA dispute with Bavarian Nordic (BN) is underway at the International Trade
Commission (ITC) in Washington.
During the period, we reached the advanced stages of pursuing a major
acquisition, which ultimately was not successful. This resulted in a one-off
charge to administration expenses, referenced in 'Trading results' below. We
continue to review further opportunities to expand our pipeline and/or our
operations.
I have now been a member of Acambis' Board for over 10 years and Chairman for
more than seven of those years. Based on good corporate governance practices, I
have decided that I will stand down from the Board and as Chairman of Acambis
later in the year and will announce the appointment of my successor at that
time. Acambis is a very different company now from when I joined the Board and I
am pleased to have played a part in its growth during that time. I am confident
that it will continue to go from strength to strength and wish its Board, our
employees and our shareholders every success.
SMALLPOX FRANCHISE UPDATE
ACAM2000: BLA submitted, warm-base manufacturing RFP received
In April, we completed submission of the ACAM2000 BLA to the US Food and Drug
Administration, which we began in January. The BLA was submitted on a "rolling"
basis under the fast-track status awarded to the programme by the FDA. Based on
a priority review status, we anticipate the FDA will complete its review before
the end of this year.
We are in active discussions with the US Centers for Disease Control and
Prevention (CDC) and the scope of work required to provide the US Government
with a warm-base manufacturing capability. Warm-base manufacturing is intended
to maintain our facilities on a long-term basis in a state of readiness to
produce doses of ACAM2000. We reported in September 2005 that the CDC had
indicated to us that it would be proceeding with a warm-base manufacturing
contract during US Government Fiscal Year 2006, which runs through to 30
September 2006. We continue to be on track to achieve that timeline.
MVA3000: procurement process continues, ITC hearing underway
In October 2005, we submitted our response to a US Government RFP to procure a
stockpile of MVA smallpox vaccine. We are continuing to progress through the
negotiation stage of the procurement process, recently submitting our responses
to the Department of Health and Human Services' technical and business
questions. Based on indications received from the US Government, we now expect
the award of contract(s) to be made around the end of the second quarter of this
year.
In the ongoing litigation with BN regarding MVA, the hearing at the ITC
commenced yesterday (8 May 2006) and is scheduled to continue through to 17 May.
Of the three courts to which BN submitted complaints, the ITC is the first to
hold a hearing.
In advance of the ITC hearing, all parties submitted Motions for Summary
Determination to the judge presiding over the ITC case. As a result, the judge
ordered the termination of BN's trade secrets claim. This initial determination
may be subject to Commission review. The termination was based on a question of
jurisdiction as the confidential disclosure agreement that was signed between
Acambis and BN in February 2002 contains a mandatory arbitration clause
requiring any such disputes between the two companies to be settled in
arbitration in Frankfurt, Germany under the rules of the International Chamber
of Commerce.
In addition, the judge has determined that BN's claim that Acambis wrongfully
obtained MVA material from the National Institutes of Health and wrongfully
converted that material into MVA3000 is not part of the ITC's investigation. The
trade secrets claim continues to be part of the action brought before the
District Court of Delaware.
The initial determination terminating the investigation regarding the trade
secrets claim and other rulings by the judge have narrowed the scope of the ITC
hearing such that its entire focus is now the patent dispute, which we consider
to be the principal question in the litigation. The judge's initial
determination on the case is expected in the third quarter of 2006, after which
his decision will be reviewed by a panel of ITC Commissioners who are required
to rule on the decision by the end of November.
RESEARCH AND DEVELOPMENT UPDATE
ChimeriVax-JE: enrolment of Phase 3 trials completed ahead of schedule
In April, we announced that we had completed enrolment of subjects into both of
our pivotal Phase 3 trials of our ChimeriVax-JE vaccine against Japanese
encephalitis. More than 2,800 subjects have been enrolled into the safety and
efficacy trials, which are being conducted in Australia and the US. Enrolment in
the multi-centre trials was completed ahead of schedule.
We have now received the approvals necessary to enable us to conduct the first
of two paediatric trials in India of ChimeriVax-JE.
Clostridium difficile (C. difficile): second Phase 1 trial on track
In February, we announced preliminary results from the first of two Phase 1
trials of our vaccine candidate against C. difficile, which is a leading cause
of hospital-acquired infections. We are making good progress with our second
Phase 1 trial and have completed the enrolment of subjects. We initiated the
trial towards the end of 2005 to assess the safety and immunogenicity of the
vaccine candidate in the elderly, the main target population.
ChimeriVax-West Nile: dose-ranging component of Phase 2 trial fully recruited
We are continuing to progress the Phase 2 trial of ChimeriVax-West Nile, our
vaccine candidate against the West Nile virus. The first component of the trial,
a dose-ranging study in healthy young adults, is now fully recruited. This will
identify the optimal dose for the second stage of the trial, which is a safety
and immunogenicity study in healthy elderly subjects.
Influenza: on track for clinical trials in 2007
We are continuing pre-clinical activities on our universal pandemic influenza
vaccine and are on track to initiate our first clinical trial with the vaccine
candidate in 2007.
ARILVAX(TM)
Novartis AG has now completed its acquisition of Chiron Vaccines, which owns and
manufactures ARILVAX(TM), the yellow fever vaccine to which we have US sales
rights. Discussions about how to resolve the outstanding issues on the programme
have now transferred to representatives of Novartis.
VIVOTIF(R)
Sales of Vivotif(R), the oral typhoid vaccine to which we have North American
distribution rights, continue to be strong, in spite of the competitor vaccine
being back on the market, suggesting that we have successfully retained some of
the additional customers gained last year.
FINANCIAL REVIEW
The financial results, prepared under the Group's accounting policies based on
International Financial Reporting Standards, for the three months ended 31 March
2006 ("Q1") are presented below. The narrative reflects a comparison of our
activities in 2006 and 2005, and, unless otherwise stated, the comparative
figures in parentheses relate to the equivalent period in 2005.
Trading results
Revenue in Q1 was GBP6.0m (2005 - GBP6.0m). The main sources of revenue were our
fixed-price 155 million-dose smallpox contract with the CDC, our two contracts
with the NIAID for MVA3000 and product sales of Vivotif.
Cost of sales was GBP4.2m (2005 - GBP3.9m) and represented costs on all of the
above programmes. Our gross profit margin in Q1 was 30.0% (2005 - 35.0%).
R&D costs were in line with management expectations and consistent with the
full year guidance provided in March. Costs increased in Q1 to GBP9.8m
(2005 - GBP7.2m) as a result of the progression of our projects into later
stages of development, most notably the costs to recruit all subjects into the
Phase 3 trials for ChimeriVax-JE. In addition, process development and
manufacturing work for our R&D projects continues to be expensed to R&D costs.
Sales and marketing costs in Q1 remained at GBP0.6m (2005 - GBP0.6m).
Administrative costs increased to GBP3.2m (2005 - GBP1.1m). The majority of the
year-on-year increase related to one-off aborted acquisition costs.
The pre-tax loss increased for the period at GBP11.4m (2005 - GBP5.8m)
principally as a result of the increased R&D costs to progress the pipeline.
Balance sheet highlights
i) Cash/debtors
This quarter saw an unusually high level of cash consumption. In addition to our
normal operational expenditures, we made large payments relating to the Phase 3
trials for ChimeriVax-JE, litigation expenses relating to MVA and aborted
acquisition costs. The short-term investments and cash balance of the Group at
31 March 2006 stood at GBP49.7m (31 December 2005 - GBP68.0m). Trade and other
receivables decreased to GBP6.7m at 31 March 2006 (31 December 2005 - GBP20.6m),
in part as a result of payments received in Q1 from the NIAID, under the MVA3000
contract, for the shipment of 500,000 doses of MVA3000 vaccine.
ii) Inventory/current liabilities
Inventory levels remained constant at GBP3.6m at 31 March 2006 (31 December 2005
- GBP3.6m). Inventory principally represents work-in-progress and finished goods
in relation to our ACAM2000 and Vivotif vaccines.
Current liabilities at 31 March 2006 reduced significantly to GBP26.0m (31
December 2005 - GBP46.8m), principally due to large trade creditor payments made
during the period, most notably to Baxter for the production of the 500,000
doses of MVA3000. Our adopted method for recognising revenue under the ACAM2000
contract with the CDC, which involves the recognition of revenue in line with
the degree of completion of the contract, has historically given rise to a
difference between invoices submitted and amounts recognised as revenue. At 31
March 2006 this difference had fully unwound (31 December 2005 - GBP2.0m).
iii) Lease financing and overdraft facilities
The combined balance on our US dollar-denominated financing facilities reduced
in the three months to 31 March 2006 to GBP10.9m (31 December 2005 - GBP12.8m)
as a result of the lease-financing facility continuing to be paid down. The
balance on this facility was GBP5.3m at 31 March 2006 (31 December 2005 -
GBP7.2m). The balance on the ARILVAX(TM) overdraft facility at 31 March 2006 was
GBP4.0m (31 December 2005 - GBP4.0m). The remaining balance at 31 March 2006 was
GBP1.6m (31 December 2005 - GBP1.6m) which relates to the discounted value of
the future payments for the Rockville fill/finish facility acquired in 2005,
payable between 2006 and 2017.
BOARD CHANGES
Since the beginning of the year, there have been two changes to our Board of
Directors.
In February, we were delighted to welcome Dr Peter Fellner to the Board as a
Non-executive Director. Peter is a well-known figure in the UK biotechnology
industry, having led the development of Celltech Group plc from a small research
company into the UK's leading biotechnology company. He was Celltech's Chief
Executive Officer from 1990 to 2003 and Chairman from 2003 until its acquisition
by the Belgian biopharmaceutical company, UCB SA, in 2004. With his extensive
knowledge and experience, we believe his insight and advice will be invaluable
as we oversee the continued development of Acambis.
In April, Michael Lytton resigned from the Board after more than five years as a
Non-executive Director. Michael has made a valuable contribution to the Board
and we would like to record our thanks to him for the insight and advice that he
has brought to our discussions throughout that time.
OUTLOOK
In the coming months, we expect to make continued progress in our clinical
trials, including initiating a paediatric trial of our ChimeriVax-JE vaccine in
India, which is our initial target market. We remain confident that the
warm-base manufacturing contract will be finalised within the specified
timeframe and also look forward to a positive decision on the US Government MVA
smallpox vaccine procurement process and on the MVA dispute currently being
heard at the ITC.
Alan Smith
Chairman
-ends-
Contacts
Acambis plc Today Thereafter
Gordon Cameron, Chief Executive Officer +44 (0) 20 7831 3113 +44 (0) 1223 275 300
David Lawrence, Chief Financial Officer +44 (0) 20 7831 3113 +44 (0) 1223 275 300
Lyndsay Wright, VP, Communications and IR +44 (0) 20 7831 3113 +44 (0) 1223 275 300
Financial Dynamics
David Yates/Anna Keeble +44 (0) 20 7831 3113
About Acambis
Acambis is a leading developer of vaccines to prevent and treat infectious
diseases. Recognised internationally as the leading producer of smallpox
vaccines, Acambis is developing an investigational smallpox vaccine, ACAM2000,
and is manufacturing emergency-use stockpiles of this investigational vaccine
for the US Government and other governments around the world. It is also
developing an attenuated smallpox vaccine, MVA3000, under contracts with the US
National Institutes of Health. Acambis' US-based subsidiary Berna Products
Corporation markets Vivotif(R), the world's only licensed oral typhoid vaccine,
in North America. Acambis' investigational vaccine against Japanese
encephalitis, ChimeriVax-JE, is undergoing Phase 3 clinical testing. It also has
the most advanced investigational vaccine against the West Nile virus, which has
spread to 48 US States in the last seven years, and a vaccine against
Clostridium difficile bacteria, a leading cause of hospital-acquired infections.
Acambis is based in Cambridge, UK and Cambridge, Massachusetts, US. Its primary
listing is on the London Stock Exchange (ACM) and its shares are listed in the
form of American Depositary Receipts on NASDAQ (ACAM). More information is
available at www.acambis.com.
About ChimeriVax
Acambis' JE and West Nile vaccine candidates have been developed using its
proprietary ChimeriVax technology, which was originally developed in
collaboration with St Louis University. The ChimieriVax technology is also the
basis of a vaccine candidate against dengue fever, which has been licensed to
sanofi pasteur.
"Safe Harbor" statement under the Private Securities Litigation Reform Act of
1995:
The statements in this news release that are not historical facts are
forward-looking statements that involve risks and uncertainties, including the
timing and results of clinical trials, product development, manufacturing and
commercialisation risks, the risks of satisfying the regulatory approval process
in a timely manner, the need for and the availability of additional capital. For
a discussion of these and other risks and uncertainties see "Risk management" in
the Company's 2004 Annual Report and "Risk factors" in its Form 20-F, in
addition to those detailed on the Company's website and in the Company's filings
made with the Securities and Exchange Commission from time to time. These
forward-looking statements are based on estimates and assumptions made by the
management of Acambis and are believed to be reasonable, though are inherently
uncertain and difficult to predict. Actual results or experience could differ
materially from the forward-looking statements.
Results for the three months ended 31 March 2006
Group income statement
Three months Three months Year
ended ended ended
31 March 31 March 31 December
2006 2005 2005
(unaudited) (unaudited) (unaudited)
GBPm GBPm GBPm
Revenue 6.0 6.0 40.9
Cost of sales (4.2) (3.9) (27.6)
_____ _____ _____
Gross profit 1.8 2.1 13.3
Research and development costs (9.8) (7.2) (34.1)
Sales and marketing costs (0.6) (0.6) (2.6)
Administrative costs (3.2) (1.1) (7.7)
Other operating income: Fair value of shares - - 0.4
received for grant of licence
_____ _____ _____
Operating loss (11.8) (6.8) (30.7)
Finance income 0.6 1.2 4.0
Finance costs (0.2) (0.2) (1.0)
_____ _____ _____
Loss on ordinary activities before taxation (11.4) (5.8) (27.7)
Taxation: UK - 0.4 (1.7)
Taxation: Overseas 0.1 1.0 2.4
_____ _____ _____
Loss on ordinary activities after taxation (11.3) (4.4) (27.0)
_____ _____ _____
Basic and diluted loss per share (in pence) (10.5)p (4.1)p (25.2)p
Basic loss per ADR (in $) (note 2) $(0.36) $(0.15) $(0.87)
Weighted average number of ordinary shares in 107,266,487 107,159,049 107,211,367
issue - basic and diluted
Group balance sheet as at 31 March 2006
As at As at As at
31 March 31 March 31 December
2006 2005 2005
(unaudited) (unaudited) (unaudited)
GBPm GBPm GBPm
Non-current assets
Goodwill 14.9 15.4 14.9
Other intangible assets 4.1 4.2 4.2
Property, plant and equipment 18.9 17.9 19.8
Deferred tax asset 0.3 1.2 0.3
Financial assets: available for sale investments 0.6 - 0.6
Other non-current assets - 0.1 -
_____ _____ _____
38.8 38.8 39.8
Current assets
Inventory 3.6 5.0 3.6
Current tax assets 0.9 3.5 1.3
Trade and other receivables 6.7 8.5 20.6
Financial assets: derivative financial 0.2 - 0.1
instruments
Liquid investments 16.1 21.3 18.8
Cash and cash equivalents 33.6 73.0 49.2
_____ _____ _____
61.1 111.3 93.6
Current liabilities
Financial liabilities:
- short-term borrowings (4.0) (3.7) (4.0)
- short-term financial liabilities (5.4) (3.2) (7.2)
Trade and other payables (4.9) (6.6) (16.1)
Accruals and deferred income (6.6) (24.5) (14.1)
Income tax payable (1.8) - (3.1)
Provisions (1.8) - (2.3)
_____ _____ _____
(24.5) (38.0) (46.8)
_____ _____ _____
Net current assets 36.6 73.3 46.8
_____ _____ _____
Total assets less current liabilities 75.4 112.1 86.6
Non-current liabilities
Investment in Joint Venture (0.3) (0.3) (0.3)
Long-term financial liabilities (1.5) (5.6) (1.6)
Other non-current liabilities - (0.4) -
Deferred tax liabilities (1.8) (1.5) (1.7)
_____ _____ _____
(3.6) (7.8) (3.6)
_____ _____ _____
Net assets 71.8 104.3 83.0
_____ _____ _____
Shareholders' equity
Share capital 10.7 10.7 10.7
Share premium 98.0 97.8 98.0
Other reserves (0.9) (2.0) (0.9)
Retained earnings (36.0) (2.2) (24.8)
_____ _____ _____
Total shareholders' equity 71.8 104.3 83.0
_____ _____ _____
Group cash flow statement
Three months Three months Year
ended ended ended
31 March 31 March 31 December
2006 2005 2005
(unaudited) (unaudited) (unaudited)
GBPm GBPm GBPm
Operating activities
Loss on ordinary activities before tax (11.4) (5.8) (27.7)
Depreciation and amortisation 1.1 1.1 5.3
(Increase)/decrease in working capital (5.2) 3.3 (2.8)
Other non-cash movements (0.4) 0.2 (0.7)
Net finance costs (0.4) (1.0) (3.0)
Taxes paid (0.7) (5.2) (0.4)
_____ _____ _____
Cash flows from operating activities (17.0) (7.4) (29.3)
Investing activities
Purchase of business operations - - (1.7)
Purchase of intangibles (0.1) - (0.4)
Purchase of property, plant and equipment (0.2) (0.4) (3.7)
_____ _____ _____
Cash flows used in investing activities (0.3) (0.4) (5.8)
Financing activities
Interest element of finance lease payments (0.2) (0.2) (0.6)
Interest paid - - (0.2)
Interest received 0.7 1.1 3.8
Proceeds from issue of shares - - 0.2
Purchase of own shares - - (0.2)
Capital element of finance lease payments (1.7) (0.8) (3.3)
Purchase of liquid investments (6.1) (12.0) (34.8)
Sale of liquid investments 8.8 11.5 36.8
_____ _____ _____
Cash flows from financing activities 1.5 (0.4) 1.7
_____ _____ _____
Decrease in cash and cash equivalents (15.8) (8.2) (33.4)
Net foreign exchange difference 0.2 0.2 1.6
Cash and cash equivalents opening balance 49.2 81.0 81.0
_____ _____ _____
Cash and cash equivalents closing balance 33.6 73.0 49.2
_____ _____ _____
Reconciliation of movements in Group shareholders' equity
As at As at As at
31 March 31 March 31 December
2006 2005 2005
(unaudited) (unaudited) (unaudited)
GBPm GBPm GBPm
Retained loss for the period (11.3) (4.4) (27.0)
Gain on foreign currency exchange - 1.0 1.6
Revaluation of available for sale investments - - 0.1
Credit in respect of employee share schemes 0.1 0.2 0.8
_____ _____ _____
(11.2) (3.2) (24.5)
New share capital subscribed - - 0.2
Purchase of Treasury shares - - (0.2)
_____ _____ _____
Net decrease in shareholders' equity (11.2) (3.2) (24.5)
Opening shareholders' equity 83.0 107.5 107.5
_____ _____ _____
Closing shareholders' equity 71.8 104.3 83.0
_____ _____ _____
Notes
1. Basis of preparation
The financial information for the three months ended 31 March 2006 and 31 March
2005 is unaudited and has been prepared in accordance with the Group's
accounting policies, based on IFRS, as adopted by the European Union. IAS 34 has
not been applied in preparing these interim results. The financial information
for the year ended 31 December 2005 has also been prepared under IFRS and is
also unaudited.
This summary of results does not constitute the full financial statements within
the meaning of s240 of the Companies Act 1985. The 2005 financial statements
will be delivered to the Registrar of Companies in due course. The Notice of The
Annual General Meeting will be sent to the shareholders on 24 May 2006. The 2006
Annual General Meeting will be held on 23 June 2006.
2. Loss per ADR (basic)
Each American Depository Receipt ("ADR") represents two ordinary shares. The
basic earnings per ADR is calculated by multiplying the earnings per ordinary
share by a factor of two and then multiplying by the prevailing US dollar
exchange rate at the end of the relevant period. The exchange rates used are
1.7346, 1.8896 and 1.7168 for the three months to 31 March 2006, 31 March 2005
and year to 31 December 2005 respectively.
3. Directors' responsibility
The Directors are responsible for the maintenance and integrity of the Group's
website. The Company notes that UK legislation governing the preparation and
dissemination of financial information may differ from that required in other
jurisdictions.
SIGNATURE
Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant Peptide Therapeutics Group has duly caused this report to be
signed on its behalf by the undersigned, thereunto duly authorized.
Date: 09 May 2006 ACAMBIS PLC
By: /s/ Lyndsay Wright
Name: Lyndsay Wright
Title: VP, Communications and IR.