PAGE  1
000 B000000 05/31/2009
000 C000000 0001380936
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 6.1
000 J000000 A
001 A000000 CLAYMORE/GUGGENHEIM STRATEGIC OPP FUND
001 B000000 811-21982
001 C000000 6305053700
002 A000000 2455 CORPORATE WEST DRIVE
002 B000000 LISLE
002 C000000 IL
002 D010000 60532
003  000000 N
004  000000 N
005  000000 N
006  000000 N
007 A000000 N
007 B000000  0
007 C010100  1
007 C010200  2
007 C010300  3
007 C010400  4
007 C010500  5
007 C010600  6
007 C010700  7
007 C010800  8
007 C010900  9
007 C011000 10
008 A000001 CLAYMORE ADVISORS, LLC
008 B000001 A
008 C000001 801-000000
008 D010001 LISLE
008 D020001 IL
008 D030001 60532
008 A000002 GUGGENHEIM PARTNERS ASSET MANAGEMENT, INC.
008 B000002 S
008 C000002 801-000000
008 D010002 SANTA MONICA
008 D020002 CA
008 D030002 90401
010 A000001 CLAYMORE ADVISORS, LLC
010 B000001 84-0000000
010 C010001 LISLE
010 C020001 IL
010 C030001 60532
011 A000001 WACHOVIA CAPITAL MARKETS LLC
011 B000001 8-00000000
      PAGE  2
011 C010001 CHARLOTTE
011 C020001 NC
011 C030001 28288
011 A000002 RAYMOND JAMES & ASSOCIATES, INC.
011 B000002 8-00000000
011 C010002 ST. PETERSBURG
011 C020002 FL
011 C030002 33716
012 A000001 THE BANK OF NEW YORK MELLON
012 B000001 84-0000000
012 C010001 NEW YORK
012 C020001 NY
012 C030001 10286
013 A000001 ERNST & YOUNG LLP
013 B010001 CHICAGO
013 B020001 IL
013 B030001 60606
015 A000001 THE BANK OF NEW YORK MELLON
015 B000001 C
015 C010001 NEW YORK
015 C020001 NY
015 C030001 10286
015 E010001 X
018  000000 Y
019 A000000 N
019 B000000    0
020 A000001 GOLDMAN SACHS & CO.
020 B000001 13-5108880
020 C000001    100
020 A000002 BNP PARIBAS
020 B000002 N/A
020 C000002     27
020 A000003 MERRILL LYNCH & CO.
020 B000003 13-2740599
020 C000003     21
020 A000004 BANK OF AMERICA
020 B000004 56-0906609
020 C000004     13
020 A000005 JP MORGAN CHASE
020 B000005 13-2624428
020 C000005     12
020 A000006 BARCLAYS CAPITAL, INC.
020 B000006 N/A
020 C000006     11
020 A000007 MORGAN STANLEY & CO., INC.
020 B000007 N/A
020 C000007      5
020 A000008 MONTGOMERY SECURITIES
020 B000008 94-1701676
020 C000008      0
020 A000009 SUNTRUST SECURITIES, INC.
      PAGE  3
020 B000009 N/A
020 C000009      0
020 C000010      0
021  000000      189
022 A000001 MERRILL LYNCH & CO.
022 B000001 13-2740599
022 C000001     42457
022 D000001    222582
022 A000002 DIRECT
022 B000002 N/A
022 C000002     72303
022 D000002     87930
022 A000003 GOLDMAN SACHS & CO.
022 B000003 13-5108880
022 C000003      4498
022 D000003    136160
022 A000004 BANK OF AMERICA
022 B000004 56-0906609
022 C000004    100888
022 D000004     26047
022 A000005 LEHMAN BROTHERS INC.
022 B000005 13-3216325
022 C000005     59747
022 D000005     40924
022 A000006 MONTGOMERY SECURITIES
022 B000006 94-1701676
022 C000006     90282
022 D000006      1443
022 A000007 MORGAN STANLEY & CO., INC.
022 B000007 13-2655998
022 C000007     38312
022 D000007     41046
022 A000008 BARCLAYS BANK PLC
022 B000008 06-1031656
022 C000008     42953
022 D000008     24082
022 A000009 JP MORGAN INVT MGMT
022 B000009 13-2624428
022 C000009     20597
022 D000009     31471
022 A000010 CREDIT SUISSE FIRST BOSTON CORP.
022 B000010 13-5659485
022 C000010     29305
022 D000010     16077
023 C000000     599541
023 D000000     726795
024  000000 Y
025 A000001 HAMPTON ROADS PPV LLC
025 B000001 N/A
025 C000001 D
025 D000001     739
      PAGE  4
025 A000002 MUZINICH CBO II LTD
025 B000002 N/A
025 C000002 D
025 D000002    1231
025 A000003 AGUA CALIENTE BAND OF CAHUILLA INDIANS
025 B000003 N/A
025 C000003 D
025 D000003     932
025 A000004 NORTHGROUP PREFERRED CAPITAL CORP
025 B000004 N/A
025 C000004 D
025 D000004     913
025 A000005 SCHWAB CAPITAL TRUST I
025 B000005 N/A
025 C000005 D
025 D000005     881
025 A000006 BNP PARIBAS
025 B000006 N/A
025 C000006 D
025 D000006     875
025 A000007 SANTANDER FINANCE PREFERRED SA UNIPERSONAL
025 B000007 N/A
025 C000007 E
025 D000007     870
025 A000008 DEUTSCHE BANK CONTINGENT CAPITAL TRUST II
025 B000008 N/A
025 C000008 E
025 D000008     850
025 A000009 PROGRESSIVE CORP/THE
025 B000009 34-0963169
025 C000009 D
025 D000009     837
025 A000010 MELLON CAPITAL IV
025 B000010 N/A
025 C000010 D
025 D000010     825
025 A000011 KEYCORP CAPITAL III
025 B000011 34-0797057
025 C000011 D
025 D000011     799
025 A000012 METLIFE CAPITAL TRUST IV
025 B000012 N/A
025 C000012 D
025 D000012     780
025 A000013 WELLS FARGO CAPITAL XIII
025 B000013 N/A
025 C000013 D
025 D000013     780
025 A000014 FIFTH THIRD BANCORP
025 B000014 31-0854434
025 C000014 D
      PAGE  5
025 D000014     767
025 A000015 ALLSTATE CORP/THE
025 B000015 N/A
025 C000015 D
025 D000015     730
025 A000016 BARCLAYS BANK PLC
025 B000016 13-4075851
025 C000016 D
025 D000016     630
025 A000017 CREDIT AGRICOLE SA/LONDON
025 B000017 N/A
025 C000017 D
025 D000017     626
025 A000018 AXA SA
025 B000018 N/A
025 C000018 D
025 D000018     601
025 A000019 BLUE FIN LTD
025 B000019 N/A
025 C000019 D
025 D000019     593
025 A000020 STATE STREET CAPITAL TRUST IV
025 B000020 N/A
025 C000020 D
025 D000020     577
025 A000021 ROYAL BANK OF SCOTLAND GROUP PLC
025 B000021 N/A
025 C000021 D
025 D000021     527
025 A000022 PNC PREFERRED FUNDING TRUST I
025 B000022 N/A
025 C000022 D
025 D000022     518
025 A000023 AGFIRST FARM CREDIT BANK
025 B000023 52-1578738
025 C000023 D
025 D000023     483
025 A000024 GLOBECAT LTD
025 B000024 N/A
025 C000024 D
025 D000024     468
025 A000025 LLOYDS BANKING GROUP PLC
025 B000025 N/A
025 C000025 D
025 D000025     462
025 D000026       0
025 D000027       0
025 D000028       0
025 D000029       0
025 D000030       0
025 D000031       0
      PAGE  6
025 D000032       0
026 A000000 N
026 B000000 Y
026 C000000 N
026 D000000 Y
026 E000000 N
026 F000000 N
026 G010000 N
026 G020000 N
026 H000000 N
027  000000 N
028 A010000         0
028 A020000         0
028 A030000         0
028 A040000         0
028 B010000         0
028 B020000         0
028 B030000         0
028 B040000         0
028 C010000         0
028 C020000         0
028 C030000         0
028 C040000         0
028 D010000         0
028 D020000         0
028 D030000         0
028 D040000         0
028 E010000         0
028 E020000         0
028 E030000         0
028 E040000         0
028 F010000         0
028 F020000         0
028 F030000         0
028 F040000         0
028 G010000         0
028 G020000         0
028 G030000         0
028 G040000         0
028 H000000         0
030 A000000      0
030 B000000  0.00
030 C000000  0.00
031 A000000      0
031 B000000      0
032  000000      0
033  000000      0
035  000000      0
036 B000000      0
038  000000      0
042 A000000   0
      PAGE  7
042 B000000   0
042 C000000   0
042 D000000   0
042 E000000   0
042 F000000   0
042 G000000   0
042 H000000   0
043  000000      0
044  000000      0
045  000000 Y
046  000000 N
047  000000 Y
048  000000  1.000
048 A010000        0
048 A020000 0.000
048 B010000        0
048 B020000 0.000
048 C010000        0
048 C020000 0.000
048 D010000        0
048 D020000 0.000
048 E010000        0
048 E020000 0.000
048 F010000        0
048 F020000 0.000
048 G010000        0
048 G020000 0.000
048 H010000        0
048 H020000 0.000
048 I010000        0
048 I020000 0.000
048 J010000        0
048 J020000 0.000
048 K010000        0
048 K020000 0.000
049  000000 N
050  000000 N
051  000000 N
052  000000 N
053 A000000 N
054 A000000 Y
054 B000000 Y
054 C000000 N
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 N
054 H000000 Y
054 I000000 N
054 J000000 Y
054 K000000 N
      PAGE  8
054 L000000 N
054 M000000 Y
054 N000000 N
054 O000000 N
055 A000000 Y
055 B000000 N
056  000000 N
057  000000 N
058 A000000 N
059  000000 Y
060 A000000 Y
060 B000000 Y
061  000000        0
062 A000000 Y
062 B000000   0.0
062 C000000   0.0
062 D000000   0.0
062 E000000   0.0
062 F000000   0.0
062 G000000   0.0
062 H000000   0.0
062 I000000   0.0
062 J000000   0.0
062 K000000   0.0
062 L000000   0.0
062 M000000   0.0
062 N000000   2.7
062 O000000   0.0
062 P000000  21.3
062 Q000000  82.1
062 R000000  18.5
063 A000000   0
063 B000000 18.1
064 A000000 N
064 B000000 N
066 A000000 N
067  000000 N
068 A000000 N
068 B000000 N
069  000000 N
070 A010000 Y
070 A020000 Y
070 B010000 Y
070 B020000 Y
070 C010000 Y
070 C020000 N
070 D010000 Y
070 D020000 Y
070 E010000 Y
070 E020000 Y
070 F010000 Y
      PAGE  9
070 F020000 Y
070 G010000 Y
070 G020000 Y
070 H010000 Y
070 H020000 Y
070 I010000 N
070 I020000 N
070 J010000 Y
070 J020000 Y
070 K010000 Y
070 K020000 N
070 L010000 Y
070 L020000 Y
070 M010000 Y
070 M020000 N
070 N010000 Y
070 N020000 N
070 O010000 Y
070 O020000 Y
070 P010000 Y
070 P020000 N
070 Q010000 N
070 Q020000 N
070 R010000 Y
070 R020000 Y
071 A000000     97080
071 B000000    115140
071 C000000    166264
071 D000000   58
072 A000000 12
072 B000000    13066
072 C000000      607
072 D000000        0
072 E000000        0
072 F000000     1691
072 G000000       46
072 H000000        0
072 I000000       20
072 J000000       59
072 K000000        0
072 L000000       58
072 M000000       69
072 N000000       34
072 O000000        0
072 P000000     1460
072 Q000000      142
072 R000000       70
072 S000000      221
072 T000000        0
072 U000000        0
072 V000000        0
      PAGE  10
072 W000000      135
072 X000000     4005
072 Y000000        0
072 Z000000     9668
072AA000000        0
072BB000000     9643
072CC010000        0
072CC020000    29632
072DD010000    12333
072DD020000        0
072EE000000        0
073 A010000   1.3600
073 A020000   0.0000
073 B000000   0.0000
073 C000000   0.4900
074 A000000     1911
074 B000000        0
074 C000000        0
074 D000000   119908
074 E000000     2734
074 F000000        0
074 G000000       20
074 H000000        0
074 I000000    18228
074 J000000     4250
074 K000000        0
074 L000000     1243
074 M000000     2018
074 N000000   150312
074 O000000     2885
074 P000000      122
074 Q000000        0
074 R010000     8957
074 R020000        0
074 R030000     1112
074 R040000    24160
074 S000000        0
074 T000000   113076
074 U010000     9105
074 U020000        0
074 V010000    12.42
074 V020000     0.00
074 W000000   0.0000
074 X000000     5225
074 Y000000    62989
075 A000000        0
075 B000000   123361
076  000000    11.53
077 A000000 Y
077 B000000 Y
077 C000000 N
      PAGE  11
077 D000000 N
077 E000000 N
077 F000000 N
077 G000000 N
077 H000000 N
077 I000000 N
077 J000000 N
077 K000000 N
077 L000000 N
077 M000000 N
077 N000000 N
077 O000000 N
077 P000000 N
077 Q010000 Y
077 Q020000 N
077 Q030000 N
078  000000 N
080 A000000 ICI MUTUAL INSURANCE CO.
080 C000000     4950
081 A000000 Y
081 B000000   7
082 A000000 N
082 B000000        0
083 A000000 N
083 B000000        0
084 A000000 N
084 B000000        0
085 A000000 Y
085 B000000 N
086 A010000      0
086 A020000      0
086 B010000      0
086 B020000      0
086 C010000      0
086 C020000      0
086 D010000      0
086 D020000      0
086 E010000      0
086 E020000      0
086 F010000      0
086 F020000      0
087 A010000 COMMON STOCK
087 A020000 18385X104
087 A030000 GOF
088 A000000 Y
088 B000000 N
088 C000000 N
088 D000000 Y
SIGNATURE   STEVEN M. HILL
TITLE       CFO & TREASURER