FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * PULEO MARC MD   2. Issuer Name and Ticker or Trading Symbol PETMED EXPRESS INC [PETS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 1441 S.W. 29TH AVENUE 3. Date of Earliest Transaction (Month/Day/Year) 12/22/2005 (Street) POMPANO BEACH, FL 33069 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) ___ Form filed by One Reporting Person _X_ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common stock 12/22/2005   S V 25,000 D $ 15.01 445,286 I See Footnote (1)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
PULEO MARC MD 1441 S.W. 29TH AVENUE POMPANO BEACH, FL 33069	X
MARPUL TRUST / SOUTHPAC TRUST INTERNATIONAL, INC. P.O. BOX 11 RAROTONGA, G1 00000				Trust for Dr. Marc Puleo
SOUTHPAC TRUST INTERNATIONAL, INC. / MARPUL TRUST TRUSTEE P.O. BOX 11 RAROTONGA, G1 00000				Trustee for Marpul Trust
MARPUL INVESTMENTS LIMITED PARTNERSHIP 1441 S.W. 29TH AVE POMPANO BEACH, FL 33069				Partnership for Marpul Trust

Signatures

/s/Marc A. Puleo, M.D.		12/22/2005
**Signature of Reporting Person		Date
/s/Brian Mason, Southpac Trust International, Inc., Trustee for Marpul Trust		12/22/2005
**Signature of Reporting Person		Date
/s/Brian Mason, Managing Director, Southpac Trust International, Inc.		12/22/2005
**Signature of Reporting Person		Date
Marc A. Puleo, General Partner, Marpul Investments Limited Partnership		12/22/2005
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The reported transactions are pursuant to a pre-arranged structured sales plan that is in accordance with both the Securities and Exchange Commission's Rule 10b5-1 and the PetMed Express, Inc. insider trading policy. The shares were sold from the Marpul Investments Limited Partnership, a Nevada limited partnership. Mr. Brian Mason, Managing Director of Southpac Trust International, Inc., a corporation established under the laws of the Cook Islands, holds voting and dispositive power over the securities owned by Marpul Trust. Dr. Puleo is the sole General Partner of Marpul Investments Limited Partnership and Marpul Trust is the sole limited partner.

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