1
                               File No. 001-13252

                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                            -------------------------


                                    FORM 11-K

                                   (Mark One)

[X]     ANNUAL REPORT PURSUANT TO SECTION 15 (d) OF THE SECURITIES EXCHANGE ACT
                             OF 1934 (FEE REQUIRED)

                     For the plan year ended March 31, 2001

                                       OR

[ ]     TRANSITION REPORT PURSUANT TO SECTION 15 (d) OF THE SECURITIES EXCHANGE
                          ACT OF 1934 (NO FEE REQUIRED)

                 For the transition period from ______ to ______

A.      Full title of the plan and address of the plan, if different from that
                           of the issuer named below:

               McKesson Corporation Profit-Sharing Investment Plan

B.                 Name of issuer of the securities held pursuant to the plan
                   and the address of its principal executive office:

                              McKesson Corporation
                                 McKesson Plaza
                                 One Post Street
                             San Francisco, CA 94104
                                 (415) 983-8300


   2

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

FINANCIAL STATEMENTS, SUPPLEMENTAL SCHEDULES AND EXHIBIT

TABLE OF CONTENTS
--------------------------------------------------------------------------------




                                                                                             PAGE
                                                                                          
INDEPENDENT AUDITORS' REPORT                                                                   1

FINANCIAL STATEMENTS AS OF AND FOR THE YEARS ENDED MARCH 31, 2001 AND 2000:

  Statements of Net Assets Available for Benefits                                              2

  Statements of Changes in Net Assets Available for Benefits                                   3

  Notes to Financial Statements                                                              4-14

SUPPLEMENTAL SCHEDULES AS OF AND FOR THE YEAR
  ENDED MARCH 31, 2001:

  Schedule of Assets Held for Investment Purposes                                             15

  Schedule of Reportable Transactions                                                         16

  Schedule of Nonexempt Transactions                                                          17

EXHIBIT:

  23.1     Independent Auditors' Consent



   3

INDEPENDENT AUDITORS' REPORT


McKesson Corporation Profit-Sharing Investment Plan:

We have audited the accompanying statements of net assets available for benefits
of the McKesson Corporation Profit-Sharing Investment Plan (the "Plan"),
formerly the McKesson HBOC, Inc. Profit-Sharing Investment Plan, as of March 31,
2001 and 2000, and the related statements of changes in net assets available for
benefits for the years then ended. These financial statements are the
responsibility of the Plan's management. Our responsibility is to express an
opinion on these financial statements based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the United States of America. Those standards require that we plan and
perform the audit to obtain reasonable assurance about whether the financial
statements are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. An audit also includes assessing the accounting principles used and
significant estimates made by management, as well as evaluating the overall
financial statement presentation. We believe that our audits provide a
reasonable basis for our opinion.

In our opinion, such financial statements present fairly, in all material
respects, the net assets available for benefits of the Plan as of March 31, 2001
and 2000, and the changes in net assets available for benefits for the years
then ended in conformity with accounting principles generally accepted in the
United States of America.

Our audits were conducted for the purpose of forming an opinion on the basic
financial statements taken as a whole. The supplemental schedules listed in the
Table of Contents are presented for the purpose of additional analysis and are
not a required part of the basic financial statements, but are supplementary
information required by the Department of Labor's Rules and Regulations for
Reporting and Disclosure under the Employee Retirement Income Security Act of
1974. These schedules are the responsibility of the Plan's management. Such
schedules have been subjected to the auditing procedures applied in our audit of
the basic 2001 financial statements and, in our opinion, are fairly stated in
all material respects when considered in relation to the basic financial
statements taken as a whole.


/s/ Deloitte & Touche LLP
September 26, 2001


   4
MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

STATEMENTS OF NET ASSETS AVAILABLE FOR BENEFITS
AS OF MARCH 31, 2001 AND 2000 (IN 000'S)
--------------------------------------------------------------------------------



                                                                   2001
                                                -----------------------------------------
                                               PARTICIPANT   NON-PARTICIPANT
                                                 DIRECTED       DIRECTED
                                                ----------    -------------      PROFIT-
                                                  PLAN'S                         SHARING
                                                 SHARE OF        COMPANY       INVESTMENT
                                                  MASTER          STOCK           PLAN
                                                  TRUST           FUND            TOTAL
                                                ----------    -------------    ----------
                                                                      
ASSETS:
  Cash and cash equivalents                     $             $         408    $      408

  Investments:
    Interest in Master Trust                       648,978                        648,978
    Institutional commingled funds
    Registered investment funds
    McKesson Corporation common stock:
      Allocated stock                                               206,455       206,455
      Unallocated stock                                             227,970       227,970
                                                ----------    -------------    ----------
           Total investments                       648,978          434,425     1,083,403
                                                ----------    -------------    ----------

  Receivables:
    Contributions
    Dividends                                                           999           999
    Interest                                                              7             7
    Interfund balances
    Due from broker for securities sold                               9,226         9,226
                                                ----------    -------------    ----------
           Total receivables                             -           10,232        10,232
                                                ----------    -------------    ----------
           Total assets                            648,978          445,065     1,094,043
                                                ----------    -------------    ----------

LIABILITIES:
  Line of credit - Unallocated                                        8,000         8,000
  ESOP promissory notes payable - Unallocated                        80,998        80,998
  Dividends payable
  Accrued interest expense - Unallocated                              2,910         2,910
                                                ----------    -------------    ----------
           Total liabilities                             -           91,908        91,908
                                                ----------    -------------    ----------

NET ASSETS AVAILABLE FOR BENEFITS               $  648,978    $     353,157    $1,002,135
                                                ==========    =============    ==========





                                                                                         2000
                                               ----------------------------------------------------------------------------
                                                      PARTICIPANT                    NON-PARTICIPANT
                                                        DIRECTED                        DIRECTED
                                               ---------------------------     ------------------------------     PROFIT-
                                                                  PLAN'S                                          SHARING
                                                  HBOC           SHARE OF        COMPANY          COMPANY        INVESTMENT
                                                  FUND            MASTER          STOCK          INVESTMENT        PLAN
                                                  GROUP           TRUST            FUND             FUND           TOTAL
                                               -------------    ----------     -------------    -------------    ----------
                                                                                                  
ASSETS:
  Cash and cash equivalents                    $                $              $         979    $           1    $      980

  Investments:
    Interest in Master Trust                                       400,636                                          400,636
    Institutional commingled funds                                                                    157,281       157,281
    Registered investment funds                      186,417                                                        186,417
    McKesson Corporation common stock:
      Allocated stock                                 32,553                         230,732                        263,285
      Unallocated stock                                                              152,030                        152,030
    Participant loans                                  3,430                                                          3,430
    Money market                                      11,230                                                         11,230
                                                       2,801                                                          2,801
                                               -------------    ----------     -------------    -------------    ----------
           Total investments                         236,431       400,636           382,762          157,281     1,177,110
                                               -------------    ----------     -------------    -------------    ----------

  Receivables:
    Contributions                                      2,855                                                          2,855
    Dividends                                                                          1,099                          1,099
    Interest                                                                               5                              5
    Interfund balances                                                 995              (469)            (526)            -
    Due from broker for securities sold
                                               -------------    ----------     -------------    -------------    ----------
           Total receivables                           2,855           995               635             (526)        3,959
                                               -------------    ----------     -------------    -------------    ----------
           Total assets                              239,286       401,631           384,376          156,756     1,182,049
                                               -------------    ----------     -------------    -------------    ----------

LIABILITIES:
  Line of credit - Unallocated                                                         8,000                          8,000
  ESOP promissory notes payable - Unallocated                                         91,923                         91,923
  Dividends payable                                                                      420                            420
  Accrued interest expense - Unallocated                                               3,084                          3,084
                                               -------------    ----------     -------------    -------------    ----------
           Total liabilities                               -             -           103,427                -       103,427
                                               -------------    ----------     -------------    -------------    ----------
NET ASSETS AVAILABLE FOR BENEFITS              $     239,286    $  401,631     $     280,949    $     156,756    $1,078,622
                                               =============    ==========     =============    =============    ==========




See notes to financial statements.



                                      -2-
   5



McKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

STATEMENTS OF CHANGES IN NET ASSETS AVAILABLE FOR BENEFITS
YEARS ENDED MARCH 31, 2001 AND 2000 (in 000's)
--------------------------------------------------------------------------------



                                                                                 2001
                                              --------------------------------------------------------------------------
                                                      PARTICIPANT                  NON-PARTICIPANT
                                                       DIRECTED                       DIRECTED
                                              ---------------------------     --------------------------       PROFIT-
                                                                PLAN'S                                         SHARING
                                                 HBOC          SHARE OF        COMPANY        COMPANY        INVESTMENT
                                                 FUND           MASTER          STOCK        INVESTMENT         PLAN
                                                 GROUP           TRUST           FUND           FUND            TOTAL
                                              -----------     -----------     -----------    -----------     -----------
                                                                                              
ADDITIONS:
  Investment income:
    Net appreciation (depreciation)
      in fair value of investments            $       (48)    $   (67,484)    $    91,392    $    (9,665)    $    14,195
    Dividends and interest                         13,628           9,635           4,132                         27,395
                                              -----------     -----------     -----------    -----------     -----------
           Total investment income (loss)          13,580         (57,849)         95,524         (9,665)         41,590
                                              -----------     -----------     -----------    -----------     -----------

  Contributions:
    Participants                                   18,506          37,097                                         55,603
    Employer                                        5,584                          10,021                         15,605
                                              -----------     -----------     -----------    -----------     -----------
           Total additions                         37,670         (20,752)        105,545         (9,665)        112,798
                                              -----------     -----------     -----------    -----------     -----------

DEDUCTIONS:
  Benefits paid to participants                    16,224          74,002          46,579         41,370         178,175
  Interest expense                                                                  7,410                          7,410
  Administrative fees                                 155           3,543               2                          3,700
                                              -----------     -----------     -----------    -----------     -----------
           Total deductions                        16,379          77,545          53,991         41,370         189,285
                                              -----------     -----------     -----------    -----------     -----------

NET INCREASE (DECREASE) IN NET
  ASSETS AVAILABLE FOR BENEFITS
  BEFORE INTERFUND TRANSFERS                       21,291         (98,297)         51,554        (51,035)        (76,487)

INTERFUND TRANSFERS                              (260,577)        345,644          20,654       (105,721)             --

MERGER OF NET ASSETS AVAILABLE
  FOR BENEFITS:
  HBO & Company Profit Sharing and
    Savings Plan
  RedLine HealthCare Corporation
    Investment Savings Plan
  CookCo, Inc. 401(k) Plan
                                              -----------     -----------     -----------    -----------     -----------


NET INCREASE (DECREASE) IN NET
  ASSETS AVAILABLE FOR BENEFITS                  (239,286)        247,347          72,208       (156,756)        (76,487)
NET ASSETS AVAILABLE FOR BENEFITS:
  Beginning of Year                               239,286         401,631         280,949        156,756       1,078,622
                                              -----------     -----------     -----------    -----------     -----------

  End of Year                                 $        --     $   648,978     $   353,157    $        --     $ 1,002,135
                                              ===========     ===========     ===========    ===========     ===========




                                                                                2000
                                              ---------------------------------------------------------------------------
                                                     PARTICIPANT                   NON-PARTICIPANT
                                                       DIRECTED                         DIRECTED
                                              ---------------------------     ---------------------------      PROFIT-
                                                                 PLAN'S                                        SHARING
                                                 HBOC           SHARE OF       COMPANY         COMPANY        INVESTMENT
                                                 FUND            MASTER         STOCK         INVESTMENT         PLAN
                                                 GROUP           TRUST           FUND            FUND            TOTAL
                                              -----------     -----------     -----------     -----------     -----------
                                                                                               
ADDITIONS:
  Investment income:
    Net appreciation (depreciation)
      in fair value of investments            $   (40,209)    $    27,510     $  (864,368)    $    21,108     $  (855,959)
    Dividends and interest                         13,885           9,345           4,644                          27,874
                                              -----------     -----------     -----------     -----------     -----------
           Total investment income (loss)         (26,324)         36,855        (859,724)         21,108        (828,085)
                                              -----------     -----------     -----------     -----------     -----------

  Contributions:
    Participants                                   29,497          34,919              49                          64,465
    Employer                                       10,552                           6,226                          16,778
                                              -----------     -----------     -----------     -----------     -----------
           Total additions                         13,725          71,774        (853,449)         21,108        (746,842)
                                              -----------     -----------     -----------     -----------     -----------

DEDUCTIONS:
  Benefits paid to participants                    27,674          56,056          26,607          16,361         126,698
  Interest expense                                                                  7,850                           7,850
  Administrative fees                                  72           1,792             109                           1,973
                                              -----------     -----------     -----------     -----------     -----------
           Total deductions                        27,746          57,848          34,566          16,361         136,521
                                              -----------     -----------     -----------     -----------     -----------

NET INCREASE (DECREASE) IN NET
  ASSETS  AVAILABLE FOR BENEFITS
  BEFORE INTERFUND TRANSFERS                      (14,021)         13,926        (888,015)          4,747        (883,363)

INTERFUND TRANSFERS                                                (1,159)          2,099            (940)             --

MERGER OF NET ASSETS AVAILABLE
  FOR BENEFITS:
  HBO & Company Profit Sharing and
    Savings Plan                                  253,307                                                         253,307
  RedLine HealthCare Corporation
    Investment Savings Plan                                        26,919                                          26,919
  CookCo, Inc. 401(k) Plan                                             58                                              58
                                              -----------     -----------     -----------     -----------     -----------


NET INCREASE (DECREASE) IN NET
  ASSETS AVAILABLE FOR BENEFITS                   239,286          39,744        (885,916)          3,807        (603,079)
NET ASSETS AVAILABLE FOR BENEFITS:
  Beginning of Year                                               361,887       1,166,865         152,949       1,681,701
                                              -----------     -----------     -----------     -----------     -----------

  End of Year                                 $   239,286     $   401,631     $   280,949     $   156,756     $ 1,078,622
                                              ===========     ===========     ===========     ===========     ===========



See notes to financial statements.


                                      -3-
   6


MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------


1.   PLAN DESCRIPTION

          The following brief description of the McKesson Corporation
          Profit-Sharing Investment Plan, (the "PSIP" or the "Plan"), formerly
          the McKesson HBOC, Inc. Profit-Sharing Investment Plan, is provided
          for general information purposes only. Participants should refer to
          the Plan document for more complete information. The PSIP is a defined
          contribution plan covering all persons who have two months of service
          and are regular or part-time employees, or are casual employees
          working 1,000 hours in a year, of McKesson Corporation, formerly
          McKesson HBOC, Inc., (the "Company" or "McKesson") or a participating
          subsidiary, except those covered by a collectively bargained pension
          plan. It is subject to the provisions of the Employee Retirement
          Income Security Act of 1974 ("ERISA"). Certain administrative costs
          incurred by the PSIP are paid by the Company. The Plan is comprised of
          the following:

     A.   PROFIT-SHARING INVESTMENT PLAN

          MERGER OF HBO & COMPANY PROFIT SHARING AND SAVINGS PLAN - During
          fiscal year 1999, McKesson Corporation completed the acquisition of
          the former HBO & Company, now known as McKesson Information Solutions,
          Inc. ("MIS"), a wholly-owned subsidiary of the Company. Effective
          April 1, 1999, the net assets available for benefits of the HBO &
          Company Profit Sharing and Savings Plan (totaling $253,307,000) were
          merged into the PSIP. MIS participants (MIS employees and certain
          employees of a former MIS subsidiary) have retained their existing
          matching percentage which is different from other McKesson employees.

          TRANSFERS FROM OTHER QUALIFIED PLANS - Effective November 1, 1999, and
          March 1, 2000, the assets available for benefits of the CookCo, Inc.
          401(k) Plan (totalling $58,000) and the RedLine HealthCare Corporation
          Investment Savings Plan (totaling $26,919,000), respectively, were
          merged into the Plan.

          CONTRIBUTIONS - Participants may elect to make basic contributions
          ranging from 1%-6% of compensation, 1%-4% for MIS participants.
          Participants who make basic contributions of 6% (4% for MIS
          participants) may elect to make supplemental contributions of up to an
          additional 10% of compensation (12% for MIS participants). A
          participant's pretax contributions are limited to $10,500 per year for
          calendar years 2001 and 2000. Total contributions are limited to the
          lesser of $30,000 or 25% of taxable compensation per fiscal year.
          Additional limits may apply to individuals classified as highly
          compensated employees.

          Effective the last day of each month throughout the fiscal year,
          participants are credited with matching Company contributions, in the
          form of Company common stock, based on a percentage of their basic
          contributions. An additional annual matching contribution may be
          granted at the discretion of the Company. For the fiscal year 2001,
          the matching percentage was 70% of contributed amounts up to the first
          6% of contributions for all eligible employees of the McKesson



                                      -4-
   7

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS (CONTINUED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------


          divisions and subsidiaries, except MIS. MIS employees received 105% of
          contributed amounts up to the first 4% of contributions for eligible
          employees.

          In fiscal 2000, the total matching percentage for eligible McKesson
          employees was 50% of contributed amounts, up to 6% contributed. For
          MIS participants, the Company matched 75% of contributed amounts up to
          the first 4% contributed.

          PARTICIPANT ACCOUNTS - Each participant's account is credited with the
          participant's contribution and an allocation of the Company's
          contribution and Plan earnings. Allocations are based on participant
          earnings, or account balances, as defined. The benefit to which a
          participant is entitled is the benefit that can be provided from the
          participant's vested account.

          VESTING - Participant contributions and earnings thereon are 100%
          vested at all times. PSIP employer matching contributions vest 20%
          annually. A participant is 100% vested after five years of accredited
          service.

          INVESTMENT OPTIONS - Upon enrollment in the PSIP, a participant may
          direct their contributions in 1% increments to any of the investments
          offered to the participant's specific employee group within the Plan.
          Effective January 1, 2001, the asset manager was changed to Fidelity
          Trust and investment options expanded to include a mutual fund window
          and a brokerage window. The following are descriptions from each
          fund's prospectus or fund manager's report:

              CERTUS STABLE VALUE FUND invests in low-risk, high-quality
              fixed-income investments issued by credit-worthy life insurance
              companies and financial institutions. This is a separately managed
              account, not a mutual fund.

              DODGE & COX LARGE CAP VALUE FUND invests in the common stock of
              well-established companies when the fund managers believe the
              long-term earnings prospects are not reflected in the current
              price.

              FIDELITY MAGELLAN FUND represents shares invested in common stocks
              and other securities and investments.

              PUTNAM INTERNATIONAL GROWTH FUND Y invests primarily in a
              diversified portfolio of equity securities of companies located
              outside of the U.S.

              PUTNAM INVESTORS FUND Y invests primarily in common stocks.

              STATE STREET BALANCED FUND is a custom mix of comingled pools that
              invests 60% in State Street Global Advisors S&P 500 Index Fund and
              40% in State Street Global Advisors Bond Market Index Fund. This
              fund strives to match the total rate of return of the Lehman
              Brothers Aggregate Bond Index.

              STATE STREET BOND INDEX FUND is a comingled pool that seeks to
              provide investment results that correspond to the total return of
              the bonds in the Lehman Brothers Aggregate Bond Index.


                                      -5-
   8

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS (CONTINUED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------


              STATE STREET S&P 500 INDEX FUND is a comingled pool that invests
              in stocks in the benchmark S&P 500 Index.

              WELLINGTON SMALL CAP FUND represents shares of a registered
              investment company that invests in stocks within the market
              capitalization range of the Russell 2000 Index.

              MCKESSON CORPORATION STOCK FUND represents shares invested in
              Company stock.

              MUTUAL FUND WINDOW provides access to approximately 170 mutual
              fund options from more than 20 investment companies.

              BROKERAGE WINDOW provides access to a discount brokerage account
              which allows participants to develop a self-directed brokerage
              option. Commissions and account fees are charged to the
              participant's account as well as standard plan-related fees.

          LOANS - Participants may apply for a loan from the Plan. The total
          amount owed to the Plan by an individual participant cannot exceed the
          lowest of 50% of such participant's vested account balances, $50,000
          or the value of the participant's accounts attributable to basic,
          supplemental and rollover contributions. The loans bear interest at
          the then current prime rate of interest plus 1%. Contractual interest
          rates ranged from 6.50% to 11% in 2001 and from 8.75% to 11% in 2000.
          Loans may be repaid over a period not to exceed 5 years, except for
          residential loans which must not exceed a term of 10 years.

          PAYMENT OF BENEFITS - Participants have the right to withdraw the
          value of their vested accounts from the PSIP at the time of
          retirement, death, disability or termination of employment. In
          general, benefit payments are made in a cash lump sum. Employees may
          remain participants in the Participant Directed Funds by electing to
          receive installment payments or deferring withdrawal until a later
          date. Effective October 1, 1999, all dividends earned on Company stock
          are paid directly to the participants.

     B.   EMPLOYEE STOCK OWNERSHIP PLANS

          GENERAL - The Company Stock Fund consists of a leveraged Employee
          Stock Ownership Plan ("ESOP"). In fiscal 2001 and 2000, shares from
          ESOP I, II and III were used to fund all employer's allocations for
          the year.

             ESOP I - In January 1985, the Company amended the Plan to add a
             leveraged ESOP for the benefit of persons eligible to participate
             in the PSIP. In July 1986, the PSIP purchased from the



                                      -6-
   9

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS (CONTINUED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------


             Company 2,000,000 shares of Company common stock for $30,250,000,
             financed by a ten-year term loan from a bank, guaranteed by the
             Company. Additionally, in connection with a transaction involving
             subsidiaries of the Company completed on November 21, 1994 (the
             "PCS Transaction"), the ESOP purchased 1,087,754 additional shares
             in fiscal 1996. The Company extended the existing term of the
             outstanding loan balance from its original maturity in fiscal 1997
             to 2005.

             ESOP II - In October 1987, the Company amended the Plan to provide
             for the purchase of shares of Company common stock by the ESOP. In
             conjunction with this amendment, the PSIP purchased from the
             Company 4,200,000 common shares of Company common stock in 1987 for
             $54,900,000, financed by a fifteen-year term loan from the Company.
             Additionally, during fiscal 1996, in connection with the PCS
             Transaction, the ESOP purchased 3,036,484 additional shares of
             Company common stock.

             ESOP III - In June 1989, the Company amended the Plan to add an
             additional leveraged ESOP to provide for the PSIP-PLUS allocation.
             Certain persons who are contributing at least 2% of their total
             compensation to the PSIP are eligible to participate in PSIP-PLUS.
             In June 1989, the Plan purchased from the Company 2,849,003 shares
             of McKesson Corporation Series B ESOP Convertible Preferred Stock
             ($43.875 stated value) for $125,000,000, financed by a twenty-year
             term loan from the Company. During fiscal 1995, in connection with
             the PCS Transaction, all shares of Series B ESOP Convertible
             Preferred Stock held by the Plan were converted into 5,440,914
             shares of Company common stock. The ESOP purchased 6,259,080
             additional shares of Company common stock in fiscal 1996.

          RETIREMENT SHARE PLAN ALLOCATION - Effective January 1, 1997, the Plan
          provides for a Retirement Share Plan Allocation. The Retirement Share
          Plan Allocation, at the Company's election, may be in cash or shares
          of Company common stock. The Retirement Share Plan Allocation formula
          allocates to each eligible participant a percentage of the
          participant's compensation. Such percentage depends on the
          participant's combined age and years of service, or Retirement Share
          Plan "points" as defined in the Plan document, as of March 31.
          Employees hired after December 31, 1999, are not eligible to
          participate in the Retirement Share Plan.

          CONTRIBUTIONS AND PARTICIPANTS' ACCOUNTS - Dividends on unallocated
          ESOP I and II shares of Company common stock, plus the Company's cash
          contributions to the ESOP, are used to pay the obligations under the
          ESOP I and II loans. For the ESOP III loan, dividends on all shares of
          Company common stock (allocated to PSIP-PLUS and unallocated) plus the
          Company's cash contributions to the ESOP III are used to pay the
          obligations under the loan. Under the terms of the loan agreements,
          the Company is required to make cash contributions to each ESOP to the
          extent that the dividends are not sufficient to service the debt. The
          cash contributions amounted to $15,604,705 and $13,230,825 for the
          years ended March 31, 2001 and 2000, respectively.



                                      -7-
   10



MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS (CONTINUED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------


          The Company allocates shares to participants' accounts on the basis of
          compensation and basic contributions for the plan year. The Company
          common stock in the PSIP-PLUS is allocated to eligible participants'
          accounts on a per capita basis each year for a period of twenty years
          through fiscal 2010. Employees hired after December 31, 1999, are not
          eligible for the PSIP-PLUS.

          VESTING - Employees become vested in all PSIP allocations after five
          years of employment (20% annually over five years). Employees hired on
          or before December 31, 1996 become vested in PSIP matching
          contributions and PSIP-PLUS after three years of employment.
          Generally, 100% vesting is provided upon retirement, disability,
          death, termination of the Plan, or a substantial reduction in work
          force initiated by the Company. A rehired employee who has met certain
          levels of service prior to termination may be entitled to have
          forfeited interests in the PSIP reinstated. Each plan year, forfeited
          interests are used to reinstate previously forfeited amounts of
          rehired employees, and other plan expenses as appropriate. Forfeitures
          for the years ended March 31, 2001 and 2000 were $2,154,460 and
          $2,463,657.

          PAYMENT OF BENEFITS - Distributions are made only upon participant
          retirement, death (in which case, payment shall be made to the
          participants' beneficiary or, if none, his or her legal
          representatives), or other termination of employment with the Company.
          Distributions are made in cash or, if a participant elects, in the
          form of Company common shares plus cash for any fractional share.

          INVESTMENTS - The following ESOP information regarding the shares of
          McKesson Corporation common stock held is as of March 31 (in
          thousands):



                                                 2001                                       2000
                               ----------------------------------------   ----------------------------------------
                                NUMBER OF       COST        FAIR VALUE     NUMBER OF       COST        FAIR VALUE
                                 SHARES         BASIS        OF SHARES      SHARES         BASIS        OF SHARES
                               ----------   ------------   ------------   ----------   ------------   ------------
                                                                                    
          Unallocated               8,522       $160,820       $227,970       10,987       $207,307       $230,732
          Allocated                 7,718        190,053        206,455        7,240        188,219        152,030
                               ----------   ------------   ------------   ----------   ------------   ------------

          Total                    16,240       $350,873       $434,425       18,227       $395,526       $382,762
                               ==========   ============   ============   ==========   ============   ============


The following is a reconciliation of the allocated and unallocated shares of the
Company Stock Fund for the years ended (in thousands):



                                                                 2001                                       2000
                                                 -------------------------------------     --------------------------------------
                                                 ALLOCATED    UNALLOCATED      TOTAL       ALLOCATED    UNALLOCATED      TOTAL
                                                 ---------    -----------     --------     ---------    -----------    ----------
                                                                                                     
Net Assets (Beginning of Year)                    $174,699      $106,250      $280,949     $ 498,010     $ 668,855     $1,166,865
  Net Appreciation (Depreciation) at fair value     42,682        48,710        91,392      (300,525)     (563,843)      (864,368)
  Dividends and interest                             1,698         2,434         4,132         1,782         2,862          4,644
  Contributions
    Employer                                                      10,021        10,021                       6,226          6,226
    Participant                                                                                   49                           49
  Benefits Paid to Participants                    (46,579)                    (46,579)      (26,607)                     (26,607)
  Interest Expense                                                (7,410)       (7,410)                     (7,850)        (7,850)
  Administrative Expense                                (2)                         (2)         (109)                        (109)
  Transfers                                         20,654                      20,654         2,099                        2,099
                                                  --------      --------      --------     ---------     ---------     ----------
Net Assets (End of Year)                          $193,152      $160,005      $353,157     $ 174,699     $ 106,250     $  280,949
                                                  ========      ========      ========     =========     =========     ==========



     C.   COMPANY INVESTMENT FUND

          Effective January 1, 2001, the Company Investment Fund investment
          control became participant directed and is now included in the Master
          Trust.



                                      -8-
   11

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS (CONTINUED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------


2.   SIGNIFICANT ACCOUNTING POLICIES

     BASIS OF ACCOUNTING - The financial statements of the Plan are prepared
     under the accrual method of accounting.

     CASH EQUIVALENTS - The Plan considers all highly liquid debt instruments
     purchased with remaining maturities of less than three months to be cash
     equivalents.

     USE OF ESTIMATES - The preparation of financial statements in conformity
     with accounting principles generally accepted in the United States of
     America requires management to make estimates and assumptions that affect
     the reported amount of assets and liabilities and disclosure of contingent
     assets and liabilities at the date of the financial statements and the
     reported amounts of revenues and expenses during the period. Actual results
     could differ from those estimates.

     INVESTMENT VALUATION AND INCOME RECOGNITION - Investments are stated at
     fair value which is based on independent valuations or publicly quoted
     market prices, except for investments in the Stable Value Fund which are
     stated at contract value (or cost), plus accrued interest. Shares of
     registered investment companies are valued at quoted market prices which
     represent the net asset value of shares held by the Plan at year-end.
     Shares of McKesson Corporation common stock are valued at quoted market
     prices on March 31, 2001 and March 31, 2000.

     Purchases and sales of securities are recorded on a trade-date basis.
     Realized gains and losses from security transactions are reported on the
     average cost method. Interest income is recorded on the accrual basis.
     Dividends are recorded on the declaration date.

     A portion of the Plan's investments are in the Master Trust which was
     established for the investment of assets of the Plan and several other
     McKesson sponsored retirement plans. Each participating retirement plan
     has an undivided interest in the Master Trust.

     Amounts allocated to withdrawing participants are recorded on the Form
     5500 for benefit claims that have been processed and approved for payment
     prior to March 31, 2001, but not yet paid as of that date.


                                      -9-
   12

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS (CONTINUED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------


3.   MCKESSON CORPORATION PROFIT-SHARING MASTER TRUST

     The assets of the Master Trust are held by Chase Manhattan Bank, N.A.
     Global Securities Services ("The Trustee"). Short-term investments included
     in the Master Trust earn interest at a current short-term market rate. At
     March 31, 2001 and 2000, the Plan's ownership interest in the Master Trust
     overall was 96.78% and 93.93%, respectively. Investment income and
     administrative expenses relating to the Master Trust are allocated to the
     individual plans based on daily balances invested in each plan. The Master
     Trust assets consisted of the following at March 31, 2001 and 2000 (in
     thousands):



                                      -10-
   13

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN


NOTES TO FINANCIAL STATEMENTS (CONTINUED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------



                                                                      2001                               2000
                                                           --------------------------         ---------------------------
                                                                             PLAN'S                              PLAN'S
                                                                            OWNERSHIP                           OWNERSHIP
                                                             AMOUNT             %               AMOUNT              %
                                                           ---------        ---------         ---------         ---------
                                                                                                    
Certus Stable Value Fund:
  Cash and cash equivalents                                $  13,438                          $  17,292
  Investment contracts                                        89,858                             80,101
  Accrued income                                                  59                                408
  Accrued liabilities                                         (1,189)
  Interfund balances                                                                                790
                                                           ---------                          ---------
           Total Certus Stable Value Fund                    102,166           92.87%            98,591           90.48%
Dodge & Cox Large Cap Value Fund
 (formerly Equity Income Fund)
  Cash and cash equivalents                                    2,604                              5,370
  Investments in stock                                        84,349                            101,910
  Accrued income                                                 218                                 44
  Accrued liabilities                                            (92)
  Interfund balances                                                                            (18,829)
  Contribution receivable                                                                         1,230
  Trade payables                                                                                 (1,181)
                                                           ---------                          ---------
           Total Dodge & Cox Large Cap Value Fund             87,079           92.49%            88,544           91.55%

Fidelity Magellan Fund investments                            50,100           99.90%

Putnam International Growth Fund Y
 (formerly Putnam Int'l. Equity Fund)
  Cash and cash equivalents                                       46
  Investments in equity securities                            12,811                             14,520
  Accrued income                                                   2
  Interfund balances                                                                                980
                                                           ---------                          ---------
           Total Putnam International Growth Fund Y           12,859           97.06%            15,500           98.15%
Putnam Investors Fund Y                                          115
  Cash and cash equivalents                                        1
                                                           ---------
           Total Putnam Investors Fund Y                         116          100.00%

State Street Balanced Fund:
  Cash and cash equivalents                                      (10)
  Investments                                                 30,003                             24,557
  Interfund balances                                                                                (44)
                                                           ---------                          ---------
           Total State Street Balanced Fund                   29,993           98.01%            24,513           98.32%
State Street Bond Index Fund investments                      21,136          100.00%

State Street S&P 500 Index Fund:
  Cash and cash equivalents                                       53
  Investments in stock                                       195,648                            152,062
  Interfund balances                                                                             17,132
                                                           ---------                          ---------
           Total State Street S&P 500 Index Fund             195,701           97.08%           169,194           95.34%

Wellington Small Cap Fund:
  Cash and cash equivalents                                      591
  Investments in stock                                        19,009                             18,001
  Accrued income                                                 161
  Accrued liabilities                                           (298)
  Interfund balances                                                                                968
                                                           ---------                          ---------
           Total Wellington Small Cap Fund                    19,463           96.92%            18,969           97.49%

Mutual Fund Window investments                               104,989          100.00%

McKesson Corporation Stock
  Cash and cash equivalents                                    1,668
  Investments in stock                                        31,361
  Accrued income                                                  77
                                                           ---------
           Total McKesson Corporation Stock                   33,106          100.00%
Cash and cash equivalents                                      2,208          100.00%
Participant Loans                                             11,630           96.26%            12,264          100.00%
                                                           ---------                          ---------
Total Master Trust Assets                                  $ 670,546           96.78%         $ 427,575           93.93%
                                                           =========                          =========




                                      -11-
   14

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS (CONTINUED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------


     The Stable Value Fund contains benefit-responsive guaranteed investment
     contracts with several insurance companies carried at contract value plus
     accrued interest totaling $25,744,928 and $43,868,479 at March 31, 2001 and
     2000, respectively. The guaranteed rates range from 5.24% to 7.72% and the
     contracts mature at various dates through September 2006. The Stable Value
     Fund also includes synthetic investment contracts which are
     benefit-responsive and are carried at contract value plus accrued interest
     totaling $64,153,634 and $39,177,808 at March 31, 2001 and 2000,
     respectively. Contract crediting rates ranged from 5.26% to 7.29% at March
     31, 2001. There are no reserves against contract value for credit risk of
     the contract issuer or otherwise. Certain of the contracts contain
     limitations on contract value guarantees for liquidation other than to pay
     benefits. The contracts mature at various dates through April 2004. The
     Plan's investment guidelines require these contracts to be with companies
     rated AA- or better, with no more than 10% of the pool invested with one
     traditional Guaranteed Income Contract issuer and no more than 40% invested
     with any one synthetic wrap provider.

     The Master Trust's investment income for the years ended March 31, was as
     follows (in thousands):



                                                      2001                               2000
                                         -------------------------------    -------------------------------
                                         Net Appreciation                   Net Appreciation
                                          (Depreciation)     Dividends &     (Depreciation)     Dividends &
                                         in fair value of     Interest      in fair value of     Interest
                                          Investments        Income          Investments        Income
                                         ----------------    -----------    ----------------    -----------
                                                                                    
     Certus Stable Value Fund                $    (20)         $ 5,795           $     -          $5,780

     Dodge & Cox Large Cap Value Fund          12,403            3,103            (7,414)          2,951

     Fidelity Magellan Fund                    (7,093)

     Putnam International Growth Fund Y        (4,000)              10             4,805               8

     Putnam Investors Fund Y                       (3)

     State Street Balanced Fund                (2,344)                             2,366

     State Street Bond Index Fund                 443

     State Street S&P 500 Index Fund          (42,456)                            22,600               8

     Wellington Small Cap Fund                 (1,798)             242             5,370             161

     Mutual Fund Window investments           (12,445)             295

     McKesson Corporation Stock               (10,845)             167

     Loans                                                         430                               883
                                             --------          -------           -------         -------
     Total                                   $(68,158)         $10,042           $27,727          $9,791
                                             ========          =======           =======         =======


     Effective January 1, 2001, the HBO Fund Group merged with the Master Trust.

4.   INVESTMENTS

     The recorded values of individual investments that represent 5% or more of
     the Plan's net assets at March 31, 2001 and 2000 were as follows (in
     thousands):



                                                    2001                2000
                                                  --------            --------
                                                                
     Interest in Master Trust                     $648,978            $401,631
     Fidelity Magellan Fund                             --              65,006
     McKesson Corporation stock                    434,425             382,762
     S&P 500 Index II Fund                              --             131,419


5.   ESOP PROMISSORY NOTES PAYABLE

     The ESOP I(b) promissory note supporting the July 1986 stock purchase is
     payable to Wells Fargo Bank in increasing annual installments (ranging from
     2% to 3% of original principal) over an 18-year term beginning in fiscal
     1987 through fiscal 2005 (Note 1,B). The interest rate is the London
     Interbank Offered Rate ("LIBOR") plus .4%, with an option to the Plan to
     fix the LIBOR rate for a period ranging



                                      -12-
   15

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS (CONTINUED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------


     from 1 month to 1 year. On March 31, 2001, the interest rate was 5.9%, and
     the outstanding balance was $3,456,408 ($4,190,142 at March 31, 2000). The
     note is guaranteed by the Company, without recourse to the participants'
     accounts, and is collateralized by 490,612 unallocated shares of McKesson
     Corporation common stock remaining from 3,087,754 shares.

     The ESOP II promissory note is payable to the Company in increasing annual
     installments (ranging from 4% to 11% of original principal) over a
     fifteen-year term beginning in fiscal 1988 through fiscal 2003. The
     interest rate is 77.5% of the prime rate or 89.08% of LIBOR, with an option
     to the borrower to fix the LIBOR rate for a period ranging from 1 month to
     1 year. On March 31, 2001, the interest rate was 4.53%, and the outstanding
     balance was $11,408,220 ($16,491,960 at March 31, 2000). This note is
     collateralized by 1,653,989 unallocated shares of McKesson Corporation
     common stock remaining from 7,236,484 shares.

     The ESOP promissory note supporting the ESOP III purchase is payable to the
     Company in increasing annual installments (ranging from 3% to 8% of
     original principal) plus interest at 8.6% over a twenty-year term beginning
     in fiscal 1990 through fiscal 2010. On March 31, 2001, the outstanding
     balance of the note was $66,133,526 ($71,240,925 at March 31, 2000). This
     note is collateralized by 5,739,745 unallocated shares of McKesson
     Corporation common stock remaining from 11,699,994 shares.

     Future minimum principal payments required on the ESOP notes are as follows
     (in thousands):

     
                                                    
     2002                                              $11,823
     2003                                               12,802
     2004                                                7,465
     2005                                                8,102
     2006                                                7,781
     Thereafter                                         33,025
                                                       -------

     Total                                             $80,998
                                                       =======


6.   LINE OF CREDIT

     In 1998, the Plan obtained a $35 million line of credit with ABN AMRO Bank
     N.V. in order to refinance a portion of the principal payable under the
     ESOP loans. The line of credit was obtained in order to reduce the number
     of shares necessary to fund the employee benefits. The Plan released only
     the shares required to fund the annual ESOP benefits. The interest rate is
     the LIBOR rate multiplied by the applicable LIBOR adjustment. The loans
     mature on June 1, 2009. At March 31, 2001 and 2000, interest rates ranged
     from 4.50% to 4.73% and from 5.26% to 5.46% on the outstanding balance of
     $8,000,000, in both years. The loans are collateralized by 637,895
     unallocated shares of McKesson Corporation common stock.



                                      -13-
   16

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

NOTES TO FINANCIAL STATEMENTS (CONCLUDED)
YEARS ENDED MARCH 31, 2001 AND 2000
--------------------------------------------------------------------------------

     The Internal Revenue Service ("IRS") has indicated it is currently unable
     to issue a ruling in regard to the refinancing agreement. If the IRS does
     not approve the refinancing, the Plan will release the shares and allocate
     them to participants as originally scheduled.

7.   TAX STATUS

     The IRS has determined and informed the Company by letter dated October 27,
     1998, that the Plan is qualified and the trust established under the Plan
     is tax-exempt, under the appropriate sections of the Internal Revenue Code.
     The Plan has been restated (effective April 1, 1999 and January 1, 2001)
     since receiving the determination letter. However, the Plan administrator
     believes that the Plan is currently designed and being operated in
     compliance with the applicable requirements of the Code. Therefore, the
     Plan administrator believes that the Plan was qualified and the related
     trust was tax-exempt as of the financial statement date.

     The plan sponsor has recently conducted an operational audit of the Plan
     and has determined that there may be certain prohibited transactions
     involving the Plan which must be corrected. The plan sponsor is in the
     process of reviewing these matters in an effort to determine the actual
     amounts involved. As soon as this review is completed, the plan sponsor
     will promptly take required corrective action. The matters under review
     include late deposit of 401(k) contributions and the payment of certain
     administrative expenses by the Plan. The plan sponsor does not believe that
     the amounts involved in any such matters are of a material nature in the
     aggregate.

8.   PLAN TERMINATION

     The Company's Board of Directors reserves the right to terminate the Plan.
     If termination should occur, all participants will immediately vest and
     each would receive a distribution equal to his or her vested account
     balance, and the unallocated common stock would be liquidated to repay the
     ESOP promissory notes payable. If the stock liquidation is insufficient to
     satisfy the notes payable, the Company would fund the difference.

9.   PENDING LITIGATION

     On November 24, 1999, an action entitled Chang v. McKesson HBOC, Inc. et
     al. (Case No. C-00-20030 RMW) ("Chang"), was filed in the U.S. District
     Court, Northern District of California. By order dated February 7, 2000,
     Chang was coordinated with the more than 50 related class actions pending
     in the United States District Court for the Northern District of
     California. On June 28, 2001, plaintiffs filed a First Amended Complaint
     naming as defendants, the Company, HBOC, certain current or former officers
     or directors of the Company or HBOC and the Chase Manhattan Bank. The
     Amended Complaint is purportedly brought on behalf of participants in the
     McKesson Corporation Profit Sharing Investment Plan and the former HBOC
     Profit Sharing and Savings Plan. Plaintiffs allege that defendants breached
     their fiduciary duties and violated sections of the Employee Retirement
     Income Security Act of 1974, causing damages to class members in connection
     with the decline in the Company's stock price following the April 28, 1999
     announcement regarding accounting improprieties at HBOC. Plan management
     does not believe it is feasible to predict or determine the outcome or
     resolution of these proceedings.

                                     ******



                                      -14-
   17

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

SCHEDULE OF ASSETS HELD FOR INVESTMENT PURPOSES
MARCH 31, 2001 (in 000's)
--------------------------------------------------------------------------------



INVESTMENT                   COST BASIS      UNITS             FAIR VALUE
----------                   ----------      ------            ----------
                                                      
McKesson Corporation
  Common Stock                $350,873       16,240              $434,425

Total


Note: In addition, McKesson Corporation common stock is held in the Master
      Trust and disclosed in the Form 5500.


                                      -15-
   18

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN


SCHEDULE OF REPORTABLE PLAN TRANSACTIONS
YEAR ENDED MARCH 31, 2000 (in 000's)
--------------------------------------------------------------------------------



                                   PURCHASES             SALES/DISPOSITIONS
                               -----------------      -------------------------          GAIN/
   IDENTITY OF ISSUE           NUMBER     AMOUNT      NUMBER          AMOUNT            (LOSS)
   -----------------           ------     ------      -------      ------------      ------------
                                                                      
SINGLE TRANSACTION
S&P 500 Index II Fund                                   376          $ 82,396          $ 38,846




                                      -16-
   19

MCKESSON CORPORATION
PROFIT-SHARING INVESTMENT PLAN

SCHEDULE OF NONEXEMPT TRANSACTIONS
YEAR ENDED MARCH 31, 2001
--------------------------------------------------------------------------------


     The plan sponsor has recently conducted an operational audit of the Plan
     and has determined that there may be certain prohibited transactions
     involving the Plan which must be corrected. The plan sponsor is in the
     process of reviewing these matters in an effort to determine the actual
     amounts involved. As soon as this review is completed, the plan sponsor
     will promptly take required corrective action. The matters under review
     include late deposit of 401(k) contributions and the payment of certain
     administrative expenses by the Plan. The plan sponsor does not believe that
     the amounts involved in any such matters are of a material nature in the
     aggregate.



                                      -17-
   20

                                   SIGNATURES
                                   ----------


Pursuant to the requirements of the Securities Exchange Act of 1934, the Plan
administrator has duly caused this annual report to be signed on its behalf by
the undersigned hereunto duly authorized.

                             McKesson Corporation Profit-Sharing Investment Plan


                             By: /s/   Paul E. Kirincic
                                 ---------------------------
                             Paul E. Kirincic
                             Senior Vice President
                             Human Resources


DATE: September 27, 2001